SubjectsSubjects(version: 964)
Course, academic year 2024/2025
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Internet and bioinformatics - MC250P07B
Title: Internet a bioinformatika
Czech title: Internet a bioinformatika
Guaranteed by: Department of Biochemistry (31-250)
Faculty: Faculty of Science
Actual: from 2024
Semester: both
E-Credits: 3
Hours per week, examination: 2/1, Ex [HT]
Capacity: 21
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: Czech, English
Explanation: V LS vyučováno v českém jazyce, v ZS v anglickém.
Note: enabled for web enrollment
you can enroll for the course in winter and in summer semester
Guarantor: Mgr. Petr Jeřábek, Ph.D.
Teacher(s): Mgr. Petr Jeřábek, Ph.D.
doc. RNDr. Václav Martínek, Ph.D.
Annotation -
The subject is lectured in English during the winter semester and in Czech during the summer semester!

The course teaches the use of internet databases and computational tools that are useful for biochemists. It covers structural analysis of biomolecules using the PyMol program. The second part of the course covers the most significant protein and DNA databases, along with basic bioinformatics tools. It includes comparing protein and DNA databases, searching for related proteins, and detecting key amino acids for protein function. The course also covers the use of the ChemSketch program for drawing chemical structures, as well as the introduction of the most important bibliographic databases and the Zotero citation manager.

Please note that due to the course being taught in a computer room, capacity is limited.
Last update: Jeřábek Petr, Mgr., Ph.D. (14.02.2024)
Aim of the course -

The course is aimed to help students to be well oriented in Internet databases and to show where and how to mine reliable and relevant information.

Last update: HPTEST/NATUR.CUNI.CZ (23.11.2009)
Literature -

Software manuals and on-line help are recommended study sources for the course.

Last update: Jeřábek Petr, Mgr., Ph.D. (14.02.2024)
Requirements to the exam -

During the final practical exam, students are allowed to use internet sources of information, including personal notes, books, and search engines, to solve test tasks.

Last update: Jeřábek Petr, Mgr., Ph.D. (14.02.2024)
Syllabus -

- Visualization of biomolecules using the PyMol program


- Protein and DNA databases (Uniprot, GenBank, etc.)


- Basic bioinformatics tools (BLAST, comparison of DNA and protein sequences in the Jalview program)


- Structural databases (Protein Data Bank, etc.)


- Drawing chemical structures in the ChemSketch program


- Bibliographic databases (PubMed, Web of Science, etc.) and Zotero citation manager

Last update: Jeřábek Petr, Mgr., Ph.D. (14.02.2024)
Learning outcomes -
  •  The student visualizes biomolecules using PyMol.
  •  The student searches for information in protein and DNA databases such as UniProt and GenBank.
  •  The student uses basic bioinformatics tools such as BLAST to compare DNA and protein sequences in Jalview.
  •  The student analyzes data from structural databases such as the Protein Data Bank.
  •  The student draws chemical structures in ChemSketch.
  •  The student searches for scientific articles in bibliographic databases such as PubMed and Web of Science and uses the Zotero citation manager.
Last update: Martínek Václav, doc. RNDr., Ph.D. (30.09.2024)
 
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