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Glycoconjugates and immunochemistry - MC250P04

Title:	Glykokonjugáty a imunochemie
Czech title:	Glykokonjugáty a imunochemie
Guaranteed by:	Department of Biochemistry (31-250)
Faculty:	Faculty of Science
Actual:	from 2019
Semester:	summer
E-Credits:	2
Examination process:	summer s.:
Hours per week, examination:	summer s.:2/0, Ex [HT]
Capacity:	unlimited
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
State of the course:	cancelled
Language:	Czech
Note:	enabled for web enrollment

Guarantor:	RNDr. Petr Pompach, Ph.D.
Is incompatible with:	MC250P04N

Opinion survey results Examination dates Schedule

Files		Comments	Added by
	L1_Introduction_historical background_glycoproteins.pdf		RNDr. Petr Pompach, Ph.D.
	L2_N_glycans_O_glycans_for_SIS.pdf		RNDr. Petr Pompach, Ph.D.
	L4_Glycans_in_different_organisms.pdf		RNDr. Petr Pompach, Ph.D.
	L5_Lectins.pdf		RNDr. Petr Pompach, Ph.D.
	L6_Analytical_methods_for_detection_and_characterization_of_glycoproteins.pdf		RNDr. Petr Pompach, Ph.D.
	L7_Glycoconjugates_and_diseases.pdf		RNDr. Petr Pompach, Ph.D.

Annotation -

Last update: RNDr. Petr Pompach, Ph.D. (17.09.2013)

The series of lectures „Glycoconjugate and Immunochemistry“ include the actual knowledge in the field of glycoproteins, glycolipids, proteoglycans and other glycoconjugates and their biological and biochemical aspects, biosynthesis, and roles in different diseases. Methods for detection and characterization of glycoproteins and glycopeptides are discussed as well. The second part of the lectures is focused on basic immunochemistry including description of basic terms of immunology, function of immune system and its role in diseases. Basic methods used in immunology are also summarized.
Lectures are in Czech, slides in English.

Literature - Czech

Last update: RNDr. Petr Pompach, Ph.D. (03.10.2013)

Literatura: Essentials of Glycobiology, 2nd edition, Edited by Ajit Varki, Richard D Cummings, Jeffrey D Esko, Hudson H Freeze, Pamela Stanley, Carolyn R Bertozzi, Gerald W Hart, and Marilynn E Etzler.

Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009.

Elektronická verze: http://www.ncbi.nlm.nih.gov/books/NBK1908/

Základy Imunologie 2. vydání; Václav Hořejší, Jiřina Bartůňková, TRITON 2001

Requirements to the exam - Czech

Last update: RNDr. Petr Pompach, Ph.D. (17.09.2013)

Písemná nebo ústní zkouška v rozsahu sylabu

Syllabus -

Last update: RNDr. Petr Pompach, Ph.D. (17.09.2013)

Introduction to glycoconjugates, historical background, saccharides and their structure, chemical reactions of glycans. N-glycans and O-glycans (biosynthesis, functions, structure). Other glycoconjugates (glycosphingolipids, GPI, hyaluronan, proteoglycans, glycosaminoglycans). Glycoproteins in different organisms. Lectins. Glycoconjugates and diseases. Analytical methods for detection and characterization of glycoproteins. Immunochemistry, historical overview and basic terms. Immunity system and its compartments. Immunity system in diseases. Methods in imunology.