SubjectsSubjects(version: 901)
Course, academic year 2022/2023
  
Biochemistry - MC250P03I
Title: Biochemie I
Czech title: Biochemie I
Guaranteed by: Department of Biochemistry (31-250)
Faculty: Faculty of Science
Actual: from 2020
Semester: winter
E-Credits: 4
Examination process: winter s.:
Hours per week, examination: winter s.:4/0 Ex [hours/week]
Capacity: 0
Min. number of students: unlimited
Virtual mobility / capacity: no
State of the course: taught
Language: Czech, English
Is provided by: MC250P03C
Explanation: v roce 2020/21 jen v ZS a pouze pro repetenty, výuka je v rámci MC250P03C
Guarantor: prof. RNDr. Petr Hodek, CSc.
Teacher(s): RNDr. Helena Dračínská, Ph.D.
prof. RNDr. Petr Hodek, CSc.
RNDr. Tomáš Ječmen, Ph.D.
Mgr. Petr Jeřábek, Ph.D.
Mgr. Božena Kubíčková, Ph.D.
Incompatibility : MC250P03C
Is incompatible with: MC250P03C
Opinion survey results   Examination dates   Schedule   
Annotation -
Last update: prof. RNDr. Petr Hodek, CSc. (06.05.2022)
The course covers the whole area of a basic biochemistry. The lectures are largely based on the explanation why and how the chemicals undergo enzyme catalyzed reactions. Particular metabolic pathways are presented in the context of the entire metabolism. The structure-function relationships of involved chemical compounds is emphasized.

Lectures are provided to Czech students in Czech. The course for Erasmus students is in English. Depending on the number of enrolled students, the course is organized in the form of lectures or in another way (colloquia, consultations).
Literature -
Last update: prof. RNDr. Petr Hodek, CSc. (06.05.2022)

RECOMMENDED:

D. L. Nelson, M. M. Cox: Lehninger's Principles of Biochemistry, 5th Edition, W. H. Freeman and Comp., New York, 2008.
J. Koolman, K. H. Roehm: Color Atlas of Biochemistry, 3rd Edition, Thieme, Stuttgart, New York 2013.
D. Voet, J. G. Voet: Biochemie, 3rd Edition, Victoria Publishing, 1995.
J. M. Berg, J. L. Timoczko, L. Stryer: Biochemistry, 7th Edition, W. H. Freeman and Comp., New York 2011.

Requirements to the exam -
Last update: prof. RNDr. Petr Hodek, CSc. (06.05.2022)

The exam is written, oral or combined according to the student's vote at the first lecture. Knowledge of static, dynamic and informational biochemistry is required in the scope of Handouts for the Course provided in SIS or http://zaklady-biochemie.wz.cz/.

Syllabus -
Last update: prof. RNDr. Petr Hodek, CSc. (06.05.2022)

SYLLABUS:

Amino acids and peptides. Protein structure and function. Enzymes: mechanism of enzyme action, control of enzymic activity. Carbohydrates and their metabolism. Lipids. Biological membranes and membrane transport. DNA and RNA. Flow of genetic information. RNA synthesis and splicing. Protein synthesis. Citric acid cycle. Fatty acid metabolism. Oxidative phosphorylation. Photosynthesis. Biosynthesis of membrane lipids and steroid hormones. Biosynthesis of amino acids and heme. Biosynthesis of nucleotides. Amino acid degradation and the urea cycle. Hormones and their action. 

LITERATURE:

D.L.Nelson, M.M. Cox: Lehninger's Principles of Biochemistry, 5th Edition, W.H.Freeman and Comp., New York, 2008; Koolman J, K. H. Roehm: Color Atlas of Biochemistry, 3rd Edition, Thieme, Stuttgart, New York 2013; Voet D., Voet JG., Biochemistry, 3rd Edition, Victoria Publishing, 1995; Berg, Timoczko, Stryer - Biochemistry, 7rd Edition, W.H.Freeman and Company, New York 2011.

 
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