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Last update: doc. RNDr. František Půta, CSc. (06.02.2022)
covers the basics of molecular mechanisms behind the complexity, sustainability and heredity of the living organisms including evolutionary principles and phenomenon of the origin of life. It covers the biology of prokaryotes and eukaryotes emphasizing the interplay between the structure and function on the seminal topics like biosynthesis and transformation of cellular components and organelles; cell growth and oncogenic transformation; transport, receptors, and cell signaling; the cytoskeleton, the extracellular matrix, and cell movements; chromatin structure and RNA synthesis. The course From molecules to cells set the stage for follow-up courses, particularly From cells to organisms. The course is built from topical blocks (see Syllabus) each of them consisting of lecture (3h) and workshop focused on primary literature as a Q&A session(1h). |
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Last update: RNDr. Nataša Šebková, Ph.D. (31.05.2022)
1. Molecular Biology of the Cell, 7th Edition, ISBN-13: 978-0393884821, 2022 |
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Last update: doc. RNDr. František Půta, CSc. (06.02.2022)
Final mark is based on the oral examination (67%) and results of tests taken during the course (33%). Oral examination takes place during the examination period and students must first obtain the evaluation for Q&A sessions and take-home exercises. |
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Last update: doc. RNDr. František Půta, CSc. (06.02.2022)
Definition of life Origin of life Sustainability of life - metabolism Strategies of energetic metabolism Information molecules From nucleic acid to protein - central dogma of molecular biology Protein biology Concept of conformation change - regulation of enzyme activity, molecular machines Cytoskeleton and cell mobility Vesicular trafficking Cell signalling Cell cycle and its regulation E pluribus unum - general cell biology principles under specific conditions (in differentiated organism in particular cell types or separate taxa) |