Protein dynamics in development and cancer - MB151P107E
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One-semester lecture course focused on deepening of knowledge about molecular mechanisms of protein dynamics and protein stability. The main aim of the course is to understand the proteasome-ubiquitin system and its function in the regulation of cell cycle, development, immune response, autophagy or protein quality control.
Last update: Šebková Nataša, RNDr., Ph.D. (24.10.2019)
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Literature is based on contemporary summarizing articles and articles describing current important discoveries concerning the topic of individual lectures. Last update: Šebková Nataša, RNDr., Ph.D. (24.10.2019)
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Current review papers which will focus on the lectures and which will be distributed before the lectures. Last update: Šebková Nataša, RNDr., Ph.D. (24.10.2019)
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LECTURES OF WINTER SEMESTER: 1. Protein stability - introduction 2. Proteasome 3. Ubiquitin ligase 4. Regulation of protein stability in the cell cycle 5. Regulation of protein stability in development 6. Protein degradation associated with ER 7. Autophagy - lysosome 8. Protein degradation in response to cytotoxic stress 9. Summary Last update: Šebková Nataša, RNDr., Ph.D. (24.10.2019)
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Zvládnout výuku v anglickém jazyce. Zkouška je pro česky mluvící studenty vedena v češtině Last update: Šebková Nataša, RNDr., Ph.D. (21.02.2018)
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