SubjectsSubjects(version: 901)
Course, academic year 2022/2023
  
Protein dynamics in development and cancer - MB151P107E
Title: Protein dynamics in development and cancer
Czech title: Dynamika proteinů ve vývoji a rakovině
Guaranteed by: Department of Cell Biology (31-151)
Faculty: Faculty of Science
Actual: from 2019
Semester: winter
E-Credits: 3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0 Ex [hours/week]
Capacity: unlimited
Min. number of students: unlimited
Virtual mobility / capacity: no
State of the course: taught
Language: English
Note: enabled for web enrollment
Guarantor: Mgr. Lukáš Čermák, Ph.D.
Teacher(s): Mgr. Lukáš Čermák, Ph.D.
Incompatibility : MB151P107
Is incompatible with: MB151P107
Opinion survey results   Examination dates   Schedule   
Annotation -
Last update: RNDr. Nataša Šebková, Ph.D. (24.10.2019)
One-semester lecture course focused on deepening of knowledge about molecular mechanisms of protein dynamics and protein stability. The main aim of the course is to understand the proteasome-ubiquitin system and its function in the regulation of cell cycle, development, immune response, autophagy or protein quality control.
Literature -
Last update: RNDr. Nataša Šebková, Ph.D. (24.10.2019)

Literature is based on contemporary summarizing articles and articles describing current important discoveries concerning the topic of individual lectures.

Requirements to the exam -
Last update: RNDr. Nataša Šebková, Ph.D. (24.10.2019)

Current review papers which will focus on the lectures and which will be distributed before the lectures.

Syllabus -
Last update: RNDr. Nataša Šebková, Ph.D. (24.10.2019)

LECTURES OF WINTER SEMESTER:

1. Protein stability - introduction

2. Proteasome

3. Ubiquitin ligase

4. Regulation of protein stability in the cell cycle

5. Regulation of protein stability in development

6. Protein degradation associated with ER

7. Autophagy - lysosome

8. Protein degradation in response to cytotoxic stress

9. Summary

Entry requirements - Czech
Last update: RNDr. Nataša Šebková, Ph.D. (21.02.2018)

Zvládnout výuku v anglickém jazyce. Zkouška je pro česky mluvící studenty vedena v češtině

 
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