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Course, academic year 2023/2024
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Structure and Function of Cytoskeleton - MB150P67
Title: Struktura a funkce cytoskeletu
Czech title: Struktura a funkce cytoskeletu
Guaranteed by: Department of Cell Biology (31-151)
Faculty: Faculty of Science
Actual: from 2022
Semester: winter
E-Credits: 3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0, Ex [HT]
Capacity: 30
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: Czech
Explanation: prednaska se kona na UMG AVCR, vzdy v pondeli 15:30, poslucharna 3 patro
Additional information: http://www.img.cas.cz/dbc/
Note: enabled for web enrollment
Guarantor: doc. RNDr. Pavel Dráber
Teacher(s): doc. RNDr. Pavel Dráber
Annotation -
Please note, the lectures are given in czech language only.

Following topics are included in the lecture-course Cytoskeleton and membrane skeleton: organisation and function of cytoskeleton, structure and dynamics of microtubules, microtubule-associated proteins, microtubule motor proteins, microtubules and cell division, structure and dynamics of microfilaments, microfilament-associated proteins, microfilament motor proteins, microfilaments and muscle contraction, structure and dynamics of intermediate filaments, proteins associated with intermediate filaments, membrane skeleton, nuclear skeleton, interactions between cytoskeleton subsystems, cytoskeleton and signal transduction, pathological changes of cytoskeleton, methods for study structure and dynamics of cytoskeletal components. This lecture-course concentrates on animal cell models. In the course are presented experimental results from Laboratory of Biology of Cytoskeleton, Institute of Molecular Genetics, Czech Academy of Sciences.

Last update: PUTA (21.03.2006)
Literature - Czech

Molecular biology of the cell, Alberts et al., 6th edition, Garland Science 2015

Chapter 9:            Visualizing cells

Chapter 16:          The cytoskeleton

Chapter 18:          Cell cycle (mitosis)

Chapter 19:          Cell junctions and the extracellular matrix (cell-cell junctions, cell-matrix-junctions)

Last update: Šebková Nataša, RNDr., Ph.D. (21.02.2018)
Requirements to the exam - Czech

Ústní zkouška z celého rozsahu přednášené látky.

Last update: Půta František, doc. RNDr., CSc. (25.04.2012)
Syllabus - Czech

Cytoskelet úvod

 

Mikrotubuly, stavební proteiny, modifikace, struktura, nukleace, asociované proteiny, dynamická nestabilita mikrotubulů

 

Mikrofilamenta, stavební proteiny, struktura, nukleace, asociované proteiny, dynamika mikrofilament

 

Střední filamenta, stavební proteiny, struktura, asociované proteiny, dynamika středních filament

 

Interakce mezi cytoskeletálními systémy

 

Molekulární motory

 

Cytoskelet a přenos signálů

 

Membránový skelet

 

Jaderný skelet

 

Septiny

 

Cytoskelet prokaryot

Cytoskelet a choroby

 

Speciální techniky studia cytoskeletu

Last update: Šebková Nataša, RNDr., Ph.D. (21.02.2018)
Entry requirements - Czech

Zvládnout výuku v anglickém jazyce. Zkouška je pro česky mluvící studenty vedena v češtině.

Last update: Šebková Nataša, RNDr., Ph.D. (21.02.2018)
 
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