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Course, academic year 2019/2020
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Toxicology - MB150P53
Title in English: Toxikologie
Czech title: Toxikologie
Guaranteed by: Department of Physiology (31-152)
Faculty: Faculty of Science
Actual: from 2015 to 2019
Semester: winter
E-Credits: 3
Examination process: winter s.:combined
Hours per week, examination: winter s.:2/0 Ex [hours/week]
Capacity: unlimited
Min. number of students: unlimited
State of the course: taught
Language: Czech
Guarantor: RNDr. Daniela Horníková, Ph.D.
Teacher(s): RNDr. Daniela Horníková, Ph.D.
doc. RNDr. Jiří Novotný, DSc.
Annotation -
Last update: RNDr. Daniela Horníková, Ph.D. (15.03.2019)
Please note, the lectures are given in czech language only.

Specialized lecture on toxic substances and their effects on the living organisms. Facultative for all interested students of study program biology, chemistry and environmental protection.
Literature - Czech
Last update: RNDr. Daniela Horníková, Ph.D. (11.03.2019)

Toxikologie, Igor Linhart, Vysoká škola chemicko-technologická, 2014
Farmakologie a toxikologie, Heinz Lüllmann, Klaus Mohr, Martin Wehling, Grada Publishing a.s., 2004
Základní a aplikovaná farmakologie, Dagmar Lincová, Hassan Farghali, et al., Galén, 2007
Základy toxikologie: obecná toxikologie a ekotoxikologie, Jaroslav Prokeš, Galén, 2005

Requirements to the exam - Czech
Last update: RNDr. Daniela Horníková, Ph.D. (12.09.2013)

Předmět je ukončen písemným testem a ústní zkouškou.

Syllabus -
Last update: STEFL (10.04.2002)

1. Introduction to toxicology. Definitions, branch differentiation. 2. Absorption, distribution and elimination of toxic substances. 3. The influence of chemical and physical factors on the organism and its functions. 4. Interaction of chemical and physical factors. 5. Analysis of toxic substances. 6. Risk assessment. 7. QSAR - prediction of the effects of toxic substances.


Casarett and Douls´s Toxicology, 4th ed., M.O.Amdur, J.D.Doul, C.D.Klaassen, eds., Pergamon Press, 1991.

General and Applied Toxicology, B.Ballantyne, T.Marrs, P.Turner, eds, Vol.I, II., M Stockton Press, 1993.

Handbook on the Toxicology of Metals, Friberg, Nordberg, Vouk, eds., Vol.I, II., Elsevier, 1986.

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