SubjectsSubjects(version: 978)
Course, academic year 2025/2026
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Principles of Genetics - MB140P16E
Title: Principles of Genetics
Czech title: Základy genetiky
Guaranteed by: Department of Genetics and Microbiology (31-140)
Faculty: Faculty of Science
Actual: from 2025
Semester: winter
E-Credits: 5
Examination process: winter s.:combined
Hours per week, examination: winter s.:2/2, C+Ex [HT]
Capacity: 16
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: English
Note: enabled for web enrollment
priority enrollment if the course is part of the study plan
Guarantor: RNDr. Michaela Schierová, Ph.D.
Teacher(s): Ivalú Macarena Ávila Herrera, M.Sc., Ph.D.
Mgr. Martin Forman
doc. Mgr. Vladimír Hampl, Ph.D.
RNDr. Martina Johnson Pokorná, Ph.D.
doc. RNDr. Jiří Král, CSc.
RNDr. Michaela Schierová, Ph.D.
Is incompatible with: MB140P47, MB140P17
Annotation -
This course of genetics is designed for master students of Parasitology and Infection Biology. The previous basic knowledge of genetics and molecular biology is expected and will be revised during seminar. The“first aid“ will be given for students (if needed). Seminar is an integral part of the course. By solving theoretical tasks , discussions and by examining microscopic samples, you get enhanced knowledge of genetics.
Specific features of genetics of parasites and their vectors will be mentioned to complete information based on analysis in model organisms.
At the end of the course you get good knowledge of transmission genetics, cytogenetics and you will understand the principles of genome analysis and molecular taxonomy.



in 2025/26 Lectures: Monday, 9:00-10:30 and seminars: Wednesday, 14:00-15:30
The first meeting is Wednesday, 2nd October 2024




The moodle web page of the course:
https://dl2.cuni.cz/course/view.php?id=6102
Password: malaria



Last update: Schierová Michaela, RNDr., Ph.D. (16.09.2025)
Literature -

The essential study material for the exam are presentations available on Moodle.

Klug W.S., Cummings M.R., Spencer C.: Concepts of Genetics , Pearson Education, Inc., ,

Snustad D.P., Simmons M.J.: Principles of Genetics 2019 John Wiley and Sons, Inc., Hoboken,

Brooker RJ: Genetics: Analysis and Principles, 6th ed., McGraw-Hill Education, 2017

Last update: Rubešová Jana, RNDr., Ph.D. (08.06.2022)
Requirements to the exam

Evaluation criteria:
To get a credit from the course, you are required:
To attend seminars regularly (minimum 60%)
To pass successfully „Solving Problems Test“  = to get 40% points at minimum
To solve  problems during semester (at Moodle): at least 2 successfully solved (about 10 possible)

The exam is combined from written test and oral exam. Also your additional activity during semester can improve your final result. The written test  is composed of 10 questions covering all presented topics. Each  answer is rated 0 - 4 points. Only students who got at least 25 points in the written test are allowed to the oral exam (usually another day than the written test). 
At the oral exam you get 2 questions, each for 20 points (maximum).
The additional activities are: short tests at Moodle during semester (20 points maximum) and creative activity  (voluntary reviews, projects, presentations etc., for 10 points maximum)
Final mark:
1: over 85 points
2: over 70 points
3: over 55 points

To get a final mark you are required to get a credit.

Last update: Schierová Michaela, RNDr., Ph.D. (01.08.2025)
Learning outcomes

Upon completion, students will be able to:

  1. Explain core concepts in both classical genetics (e.g. Mendelian inheritance, linkage, gene mapping) and molecular genetics (DNA structure, gene expression, mutation, repair, genetic variation).
  2. Describe advanced topics such as population genetics, immunogenetics (blood groups, HLA, immune response), oncogenetics,
  3. Summarise medical and diagnostic genetics, including DNA-based diagnostics, gene therapy strategies, and genetic counselling principles.
  4. Perform calculations in genetic crosses (both Mendelian genetics, sex-linked traits, genes in genetic linkage) and population genetics (e.g. Hardy–Weinberg equilibrium, selection, genetic drift, small population effects).
  5. Critically evaluate genetic data and cases, including mutation impacts, oncogene/tumour suppressor gene roles, and diagnosing inherited conditions.
  6. Appreciate ethical dimensions of genetics (e.g. gene therapy, diagnostics, and population-level implications), demonstrating responsible scientific awareness.
      Last update: Schierová Michaela, RNDr., Ph.D. (01.08.2025)
       
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