SubjectsSubjects(version: 945)
Course, academic year 2023/2024
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Evolution and systematics of prokaryotes - MB140P14
Title: Evoluce a systematika prokaryot
Czech title: Evoluce a systematika prokaryot
Guaranteed by: Department of Genetics and Microbiology (31-140)
Faculty: Faculty of Science
Actual: from 2020
Semester: summer
E-Credits: 3
Examination process: summer s.:oral
Hours per week, examination: summer s.:2/0, Ex [HT]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: Czech
Level: specialized
Additional information: https://dl2.cuni.cz/course/view.php?id=2399
Note: enabled for web enrollment
Guarantor: RNDr. Jaroslav Nunvář, Ph.D.
Teacher(s): RNDr. Jaroslav Nunvář, Ph.D.
Annotation -
Last update: RNDr. Jaroslav Nunvář, Ph.D. (16.10.2018)
This course provides a global overview of evolution and taxonomy of prokaryotes. In the systematic part,
taxonomic approaches are presented and important taxa are described. In the evolutionary part, emphasis is put
on evolution of peculiar prokaryotic lifestyles (nutrient symbionts, pathogens). The course further focuses on
sources of evolutionary variability and evolution of defence against selective pressures of biotic nature (selfish
genetic elements, antibiotics, host immune system).
Basic courses in Microbiology and Evolutionary biology are recommended as a prerequisite.
Literature -
Last update: RNDr. Jaroslav Nunvář, Ph.D. (23.10.2019)

Books:

Madigan M.T. et al.: Brock Biology of Microorganisms (15th Edition). Pearson, 2018

Brown J.W.: Principles of Micribial Diversity. ASM Press, 2015

Rosenberg E. et al. (Eds.): The Prokaryotes (4th Edition). Springer, 2014

Whitman W.B (Ed.).: Bergey’s Manual of Systematics of Archaea and Bacteria. Wiley, 2015

 

selected recommended reviews

Requirements to the exam -
Last update: RNDr. Jaroslav Nunvář, Ph.D. (23.10.2019)

students will be evaluated on the basis of an oral exam

Syllabus -
Last update: RNDr. Jaroslav Nunvář, Ph.D. (23.10.2019)

Molecular taxonomy, prokaryotic species

prokaryotic x eukaryotic species, phylogenetic markers and their sensitivity, singlegene x multigene x whole-genome approaches

Early evolution, major branches

two prokaryotic realms and their discovery, LUCA and its predicted feaures, prokaryotic influence on early ecosystems, eukaryogenesis from archaea

Systematics I

Terrabacteria: major taxa, their evolution and distinctive traits

Systematics II

Hydrobacteria: major taxa, their evolution and distinctive traits

Sources and mechanisms of evolutionary variability

point mutations, frameshift mutations (contingency loci), IS elements, hypermutability (mutation rate, evolution of evolvability), horizontal gene transfer and mobile genetic elements

Evolution of patogenicity

evolutionary trajectory from a fre--living to pathogenic bacterium, immune evasion, obligate host association, genetically monomorpic pathogens

Evolution of defence

protection from MGE (CRISPR,RM systems), protection of MGE from host defenses, evolution of ATB resistance

Evoluce kooperace

nutritional symbioses (sap-feeding insects, hydrothermal vents, rhizobia), bioluminescent symbioses

 
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