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Last update: RNDr. Hana Konrádová, Ph.D. (25.04.2022)
acids. The course will provide the basics of experimental and computational structural biology methods. Students will get acquainted with the methods of X-ray crystallography, nuclear magnetic resonance, electron microscopy and mass spectrometry. Computational methods will include predicting protein structures (homology modelling, AlphaFold), molecular dynamics simulation, and studying the interaction of small molecules with proteins by docking methods. Students will also get familiarised with the methods of integrative structural biology. The applications of the discussed methods will be demonstrated by case studies in selected chapters of cell biology. |
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Last update: RNDr. Hana Konrádová, Ph.D. (27.04.2022)
Links to current literature will be provided |
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Last update: Ing. Roman Pleskot, Ph.D. (29.08.2023)
Taught in English, if non-Czech speaking students enrol. |