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Exercises in Organic Chemistry - GF417
Title: Řešené úlohy z organické chemie
Guaranteed by: Department of Organic And Bioorganic Chemistry (16-16120)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2025
Semester: summer
Points: 0
E-Credits: 2
Examination process: summer s.:
Hours per week, examination: summer s.:0/20, C [HS]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: Czech
Teaching methods: full-time
Level:  
Guarantor: prof. PharmDr. Kateřina Vávrová, Ph.D.
Comes under: 1.ročník 2025/26 Farmacie volitelné
Annotation -
The course is focused on expanding and deepening the knowledge of organic chemistry and applying this knowledge to the prediction of selected drug properties.
Last update: Vávrová Kateřina, prof. PharmDr., Ph.D. (28.08.2025)
Course completion requirements -
Credit is awarded for 100% attendance at seminars.
Last update: Vávrová Kateřina, prof. PharmDr., Ph.D. (01.09.2025)
Literature - Czech

Doporučená:

  • . . In McMurry, Susan. Studijní příručka a řešené příklady : k českému vydání učebnice John McMurry: Organická chemie . Praha: Vysoká škola chemicko-technologická, 2009, s. -. ISBN 978-80-7080-723-1..

Last update: Vávrová Kateřina, prof. PharmDr., Ph.D. (30.09.2025)
Syllabus -

Solved problems related to the following topics:

  • Substitution
  • Addition and elimination
  • Reactivity of carbonyl compounds
  • Reactivity of carboxyl compounds
  • Oxidation and reduction
  • Reactions of organometallic and heterocyclic compounds
  • Rearrangements, proposals for the preparation of chemical compounds
  • Structural formulas as carriers of chemical information
  • Reactivity of organic compounds – fundamental relationships between structure and reactivity, preparation of selected types of compounds
  • Prediction of chemical and physical properties of compounds based on structure and functional groups present
Last update: Vávrová Kateřina, prof. PharmDr., Ph.D. (28.08.2025)
Learning resources -
Learning outcomes -

The elective course Solved Problems in Organic Chemistry builds on the knowledge and skills acquired in the courses Organic Chemistry I and II. It develops the ability to apply theoretical knowledge of organic chemistry to solving specific problems and reaction mechanisms, as well as applying this knowledge to the prediction of selected drug properties.

After completing the course, students will be able to:

  • Distinguish and apply the principles of substitution, addition, and elimination reactions in the synthesis of organic compounds.
  • Explain the reactivity of carbonyl and carboxyl compounds in the context of nucleophilic and electrophilic reactions.
  • Describe oxidation and reduction reactions and apply them in the design of organic syntheses.
  • Solve problems related to the reactions of organometallic and heterocyclic compounds and their use in synthesis.
  • Analyze rearrangement reactions.
  • Design synthetic routes for the preparation of organic compounds from given starting materials and desired products.
  • Predict drug properties based on their chemical structure.

Specific competencies developed:
Students, based on the acquired knowledge and skills, will be able to:

  • Identify whether a given reaction is an addition, elimination, substitution, or rearrangement.
  • Identify the electrophile, nucleophile, or radical in a given reaction.
  • Decide whether the reaction will proceed and what the product will be.
  • Propose an appropriate reagent for a given reaction.
  • Design (including multi-step) synthetic schemes for the preparation of a target compound from a given starting material.
  • Discuss the course of a given reaction using resonance structures, inductive and mesomeric effects.
  • Explain the detailed reaction mechanism of a compound with a given reagent, including curved-arrow notation showing electron movements.
  • Predict the properties of a drug from its chemical structure or propose structural modifications to adjust its desired properties.
Last update: Vávrová Kateřina, prof. PharmDr., Ph.D. (05.12.2025)
 
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