General pharmaceutical chemistry - GDFCH06
Title: Farmaceutická chemie obecná
Guaranteed by: Department of Pharmaceutical Chemistry and Pharmaceutical Analysis (16-16190)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2019
Semester: both
Points: 0
E-Credits: 0
Examination process: oral
Hours per week, examination: 0/0, Ex [HT]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: Czech
Teaching methods: full-time
Level:  
Note: course is intended for doctoral students only
enabled for web enrollment
you can enroll for the course in winter and in summer semester
Guarantor: prof. PharmDr. Petr Zimčík, Ph.D.
Incompatibility : GDFCH01
Interchangeability : GDFCH01
Is incompatible with: GDFCH01
Is interchangeable with: GDFCH01
Examination dates   WS schedule   SS schedule   
Annotation -
The subject „General pharmaceutical Chemistry“ introduces the student into the area of synthetic drugs. The aim of the subject is to bring information on physico-chemical properties of drugs and approaches how to modify these properties with consequences it has for the drugs. Besides this, the stereochemical aspects of the drugs are also concerned as well as basic principles of preparations of prodrugs and general aspects of biotransformations of the drugs. The subject covers also the general parts of the pharmaceutical chemistry that include basic principles of drug nomenclature and main historical milestones of the drug development.
Last update: Zimčík Petr, prof. PharmDr., Ph.D. (07.02.2019)
Literature -

Obligatory:

  • Williams, David A. Lemke, Thomas L. (eds.). Principles of medicinal chemistry. Baltimore: Lippincott Williams & Wilkins, 2002, 1114 s. ISBN 0-683-30737-1.

  • Wilson, Charles Owens, Gisvold, Ole. Textbook of organic medicinal and pharmaceutical chemistry. Philadelphia: Lippincott Williams & Wilkins, 2004, 991 s. ISBN 0-7817-3481-9.

Recommended:

  • Lectures from Pharmaceutical chemistry I.

Last update: prepocet_literatura.php (19.09.2024)
Requirements to the exam -

The student will study the appropriate literature. The exam is oral and includes two questions from the following list:

1. Nomenclature of the drugs. Main historical milestones in the drug development.

2. Factors influencing the drug action.

3. The importance of chemical composition for drug action

4. Prodrugs

5. The importance of physico-chemical properties for drug action

6. Importance of biotransformation for the drug action.

7. Stereochemical aspects of drug action

Last update: Zimčík Petr, prof. PharmDr., Ph.D. (07.02.2019)