SubjectsSubjects(version: 941)
Course, academic year 2022/2023
   Login via CAS
Chromatographic methods in pharmaceutical analysis - GDEFA11
Title: Chromatographic methods in pharmaceutical analysis
Guaranteed by: Department of Pharmaceutical Chemistry and Pharmaceutical Analysis (16-16190)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2019
Semester: both
Points: 0
E-Credits: 0
Examination process: oral
Hours per week, examination: 0/0, Ex [HT]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Note: course is intended for doctoral students only
enabled for web enrollment
you can enroll for the course in winter and in summer semester
Guarantor: doc. PharmDr. Petra Štěrbová, Ph.D.
Interchangeability : GDEFA09
Is interchangeable with: GDEFA09
Annotation -
Last update: doc. PharmDr. Petra Štěrbová, Ph.D. (10.02.2022)
Chromatographic Methods in Pharmaceutical Analysis is aimed at utilization of chromatographic techniques in modern pharmaceutical analysis. It covers their applications in to tests in pharmacopoeias, examination of drug stability, identifications and evaluation of impurities, as well as analysis of drugs in biological materials. The main attention is paid on (ultra)high performance liquid chromatography, gas chromatography and supercritical fluid chromatography. It covers basic principles of the techniques, technical specifications, and application of the methods, troubleshooting as well as novel trends in the field.
Requirements to the exam -
Last update: doc. PharmDr. Petra Štěrbová, Ph.D. (10.02.2022)

Examination topics:

  1. Main principles, parameters and modes of separation
  2. Detection techniques coupled with chromatographic methods in pharmaceutical analysis
  3. UHPLC and HPLC in pharmaceutical analysis
  4. GC in pharmaceutical analysis
  5. SFC in pharmaceutical analysis
  6. Chromatographic methods in pharmacopeias
  7. Quantitative chromatographic analysis of drugs
  8. Development of a chromatographic method to be used in pharmaceutical analysis
  9. Validation of a chromatographic method
  10. Modern trends in stationary phases
  11. Modern trends in chromatographic instrumentations used in pharmaceutical analysis
  12. Sample preparation prior chromatographic analysis of drugs
  13. Troubleshooting in chromatographic analysis of drugs
Charles University | Information system of Charles University |