Subjects

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Statistics for bioanalytical applications - GBN012

Title:	Statistika v bioanalytických aplikacích
Guaranteed by:	Department of Biophysics and Physical Chemistry (16-16110)
Faculty:	Faculty of Pharmacy in Hradec Králové
Actual:	from 2024
Semester:	winter
Points:	0
E-Credits:	4
Examination process:	winter s.:written
Hours per week, examination:	winter s.:8/10, C+Ex [HS]
Capacity:	unlimited / unlimited (unknown)
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
Key competences:
State of the course:	taught
Language:	Czech
Teaching methods:	full-time
Teaching methods:	full-time
Level:
Explanation:	2.ZBN - akreditace
Note:	course can be enrolled in outside the study plan enabled for web enrollment

Guarantor:	doc. Dipl.-Math. Erik Jurjen Duintjer Tebbens, Ph.D.
Comes under:	2.ročník 2024/25 BLDZ

Examination dates WS schedule

Annotation -

Statistics in Bioanalytical Applications deals with classical and modern statistical methods popular in pharmaceutical research. Students will become familiar with basic statistical procedures and the resulting interpretation of results and with other procedures offered by the GraphPad software, in which specific examples from pharmacy and related fields are practiced.

Last update: Duintjer Tebbens Erik Jurjen, doc. Dipl.-Math., Ph.D. (01.10.2024)

Course completion requirements -

The subject ends with a credit test and an exam. The credit test, which is a condition for the exam, consists in performing statistical analyzes in front of a PC in the GraphPad program. The analyzes are analogous to the analyzes discussed in the seminars. The exam has only a written part - questions from the theory discussed at all lectures and seminars. This is general theoretical knowledge, no details or mathematical derivations are required. 12 test questions (4 offered answers, only 1 of them correct), at least 6 must be answered correctly to pass the exam and get a "good" grade (3). At least 8 questions must be answered correctly for a grade of "very good" (2). At least 10 questions must be answered correctly for a grade of "excellent" (3). The processing time is 40 min. Each student has the right to 3 attempts.

Last update: Duintjer Tebbens Erik Jurjen, doc. Dipl.-Math., Ph.D. (01.10.2024)

Literature -

Obligatory:

Li Wan Po, Alain. Statistics for pharmacists. London: Blackwell Sci., 1997, 252 s. ISBN 0-632-04881-6.

Box, George E. P. Hunter, J. Stuart Hunter, William Gordon. Statistics for experimenters : design, innovation, and discovery. Hoboken, N.J.: Wiley-Interscience, 2005, 633 s. ISBN 0-471-71813-0.

Last update: Duintjer Tebbens Erik Jurjen, doc. Dipl.-Math., Ph.D. (01.10.2024)

Syllabus - Czech

Sylabus predmetu:
-    descriptive statistics for quantitative and qualitative data and their visualization
-    normal and lognormal distribution, tests of (log)normality, qq-plots
-    curve fitting for nonlinear agonist/inhibitor models
-    simple and multiple linear regression
-    simple and multiple logistic regression
-    survival analysis
-    t-tests and nonparametric counterparts
-    ANOVA, one- and two-way and nonparametric counterparts
-    Chi-square and exact Fisher test
-    Correlation coefficient and autocorrelation

Last update: Duintjer Tebbens Erik Jurjen, doc. Dipl.-Math., Ph.D. (01.10.2024)