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Immunology is an integral part of a set of disciplines focused on understanding the biological nature of humans. The main aim of the course is to introduce students to the principles of the functioning of the immune system as a whole, with its role in homeostasis, both under physiological and pathological conditions. The practical implications of immunological research are also emphasized, especially in the field of medical laboratory methodology and in the prevention and therapy of a number of diseases. As graduates of the Faculty of Pharmacy have been successful in both clinical and experimental immunology, this discipline is conceived as one of the options for future professional employment.
Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (06.08.2024)
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After the completion of the lectures, the course ends with an exam. The exam consists of test questions with the possibility of choosing the correct answer or actively completing the information. The second part of the written test is to write a mini-essay (on one topic from the list of exam questions). This is followed by the oral part of the exam. The assessment of all three parts is comprehensive. Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (06.08.2024)
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Doporučená:
Last update: prepocet_literatura.php (19.09.2024)
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Přednášky, cvičení s praktickou částí, seminář, samostudium s využitím doporučené literatury a opor. Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (21.09.2023)
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• Cells of the immune system, lymphoid organs, lymphatic vessel system. • Origin and development of cells of the immune system, the principle of immunocompetence. • Non-specific immunity, humoral (complement system) and cellular (phagocytosis) • Antigens, concept of immunogenicity, antigenic determinant, hapten. • The major histocompatibility complex of man, its biological significance, basics of immunogenetics. • Antigen-specific recognition molecules, immunoglobulins, basis of antibody and T cell receptor diversity. • Antigen and antibody reactions, principles of serology. • Adaptive immunity - specific antibody and cellular immune response. • Immunological memory, principles of vaccination, composition of vaccines. • Anti-infective, anti-tumour, transplantation immunity. • Immunological tolerance, consequences of its loss. • Nonspecific immunity, phagocytosis, complement, the course of inflammation. • Regulation of immunity, cytokines, adhesion molecules, costimulatory molecules in the cooperation of cells of the immune system. • The immune system as part of structures ensuring homeostasis, communication of immune system cells. • Immunology of reproduction. • Immunodeficiencies, autoaggressive diseases, allergies, AIDS - an overview.
> Vaccination - types of vaccines, current vaccination programme
> Phagocytosis - determination of phagocyte activity
> Non-specific humoral immunity - determination of lysozyme and CRP activity
> Immunochemistry - identification and determination of immunoglobulins
> Serology - determination of specific antibodies and antigens, ELISA, immunofluorescence and similar tests
> Identification of cell surface molecules
> Histocompatibility antigens - their identification and biological importance Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (06.08.2024)
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Jílek P., Rathouská J., Úvod do imunologie, kurz Moodle, Univerzita Karlova, Farmaceutická fakulta, Katedra biologických a lékařských věd, http://dl1.cuni.cz/course/view.php?id=3605 (Imunologie (cuni.cz)) Imunologie: https://intranet.faf.cuni.cz/Studijni-materialy/Ostatni/?path=studijn%c3%ad+opory+zbio+kombi Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (21.09.2023)
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