Subjects

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Current Trends in the Development of Chemical Drugs - GAPS244

Title:	Current Trends in the Development of Chemical Drugs
Guaranteed by:	Department of Pharmaceutical Chemistry and Pharmaceutical Analysis (16-16190)
Faculty:	Faculty of Pharmacy in Hradec Králové
Actual:	from 2022
Semester:	summer
Points:	0
E-Credits:	1
Examination process:	summer s.:
Hours per week, examination:	summer s.:14/0, C [HS]
Capacity:	unknown / unknown (unknown)
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
Key competences:	critical thinking, 4EU+ Flagship 1
State of the course:	taught
Language:	English
Teaching methods:	full-time
Level:
Is provided by:	GAF244
Explanation:	(F 3.r.)
Note:	course can be enrolled in outside the study plan enabled for web enrollment

Guarantor:	PharmDr. Marta Kučerová, Ph.D.

Examination dates

Annotation -

The field of drugs, especially the synthetic ones, is rapidly evolving, which is supported by the development of computational chemistry, robotic syntheses and high-throughput screening. The course entitled Current Trends in the Development of Chemical Drugs is an optional subject intended for students of the 3rd and 4th grade, in case of interest also for postgraduate students. The subject acquaints students with new rapidly developing pharmacodynamic groups, posssibly with tools for discovery of new chemical entities such as computer-aided drug design.

Last update: Kučerová Marta, PharmDr., Ph.D. (27.09.2023)

Course completion requirements -

The passing of a credit test in the Moodle environment is a condition for passing the credit for the subject.

Last update: Kučerová Marta, PharmDr., Ph.D. (27.09.2023)

Literature -

Recommended:

Patrick, Graham L.. An introduction to medicinal chemistry. Oxford: Oxford University Press, 2017, 877 s. ISBN 978-0-19-874969-1.

Lemke, Thomas, Williams, David A. Roche, Victoria F. (eds.). Foye´s principles of medicinal chemistry. Philadelphia : Baltimore: Lippincott Williams & Wilkins, 2013, 1500 s. ISBN 978-1-4511-7572-1.

Wilson, Charles Owens, Gisvold, Ole . Textbook of organic medicinal and pharmaceutical chemistry. Philadelphia: Lippincott Williams & Wilkins, 2004, 991 s. ISBN 0-7817-3481-9.

Last update: prepocet_literatura.php (19.09.2024)

Teaching methods -

The course consists of lectures.

Last update: Kučerová Marta, PharmDr., Ph.D. (27.09.2023)

Requirements to the exam -

The course ends with a credit.

Last update: Kučerová Marta, PharmDr., Ph.D. (27.09.2023)

Syllabus -

Introduction to the subject, trends in antimicrobial therapy

New drugs in oncology

Covalent binders

New addictive drugs (designer drugs)

Photodynamic therapy

Development in the field of nucleic acids structure based therapeutics

Computer-aided drug design (CADD)

Last update: Kučerová Marta, PharmDr., Ph.D. (27.09.2023)

Learning resources -

E-learning Moodle: Current Trends in the Development of Chemical Drugs

https://dl1.cuni.cz/course/view.php?id=5769

Last update: Kučerová Marta, PharmDr., Ph.D. (27.09.2023)

Entry requirements -

Knowledge of chemistry, biochemistry and microbiology and a minimum basis of pharmacology are required

Last update: Kučerová Marta, PharmDr., Ph.D. (27.09.2023)