Pharmaceutical Technology I - GAF344
Title: Pharmaceutical Technology I
Guaranteed by: Department of Pharmaceutical Technology (16-16210)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2022
Semester: summer
Points: 0
E-Credits: 5
Examination process: summer s.:
Hours per week, examination: summer s.:56/70, C [HS]
Capacity: unlimited / unlimited (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Level:  
Note: deregister from the credit exam date if a requisite was not fulfilled
Guarantor: doc. PharmDr. Zdeňka Šklubalová, Ph.D.
Comes under: 3.ročník 2024/25 Pharmacy (EN19)
Co-requisite : GAF308, GAF339, GAF341
Incompatibility : GAF310
Interchangeability : GAF188, GAF310
Is co-requisite for: GAF250, GAF308
Is pre-requisite for: GAF346
Is interchangeable with: GAF310
Examination dates   
Annotation -
The compulsory subject in the 3rd section of study of Pharmacy. Pharmaceutical technology 1 education is focused on dosage forms formulation with emphasis on their classification, properties and the use of excipients, elucidating composition and structure of dosage forms in technological and biopharmaceutical context. The practical training enable students to gain the basic skills necessary for compounding of preparations in pharmacies as well as in the large-scale manufacturing and the evaluation of properties of pharmaceutical products. Pharmaceutical Technology 1 presents the use of excipients, specific pharmaceutical manufacturing procedures and quality control methods for dosage forms.
Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (04.12.2021)
Course completion requirements -

 For the credit:

  • practical training and seminars - 100% presence
  • reports from practical training
  • 75% correct in tests

The subject is concluded by passing the exam and it is included in the Final State Examination.

 

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (18.12.2017)
Literature -

Obligatory:

  • Banker, Gilbert S., Rhodes, Christopher T., (eds.). Modern pharmaceutics. New York: Marcel Dekker, 2002, 838 s. ISBN 0-8247-0674-9.

  • Allen, Loyd V. (ed.). Science and practice of pharmacy. London ; Philadelphia: Pharmaceutical Press, 2013, 2 s. ISBN 978-0-85711-062-6.

  • Swarbrick, James, (ed.). Encyclopedia of pharmaceutical technology. Boca Raton: CRC Press, 2013, s. ISBN 978-18-418-4819-8.

Last update: prepocet_literatura.php (19.09.2024)
Teaching methods -

lecture

seminar

practical training

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (18.12.2017)
Requirements to the exam -

The confirmation of  credits from SIS

 

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (18.12.2017)
Syllabus -

1) Dosage Forms

  • Dosage forms and their classification

  • Pharmaceutical excipients

  • Biopharmaceutical principles in dosage forms

  • Pharmaceutical dispersion systems

  • Liquid dosage forms

  • Semisolid dosage forms

  • Solid dosage forms

  • Sterile dosage forms

  • Inhalation preparations

  • Modified release drug delivery systems

    Targeted drug delivery systems

2) Manufacturing operations in pharmaceutical technology

  • Water production

  • Filtration

  • Comminution. Milling

  • Mixing. Homogenization

  • Drying, Freeze Drying

  • Sterilization

    3) Quality control and stability of dosage forms

  • Good manufacturing practice

  • Stability of dosage forms.

  • Pharmaceutical packaging

  • Uniformity of dose

  • Disolution tests

  • Granulometry

  • Rheology

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (01.10.2021)
Learning resources -

Web FaF:

https://intranet.faf.cuni.cz/Study-materials/KFT/?path=pharmaceutical+technology

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (18.12.2017)