Biology of Tumor Cells - FV111

• Title: Biology of Tumor Cells
• Guaranteed by: Department of Medical Biology and Genetics (15-120)
• Faculty: Faculty of Medicine in Hradec Králové
• Actual: from 2022
• Semester: summer
• Points: 0
• E-Credits: 2
• Examination process: summer s.:
• Hours per week, examination: summer s.:24/6, C [HT]
• Capacity: 20
• Min. number of students: 5
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Note: course can be enrolled in outside the study plan; enabled for web enrollment
• Guarantor: prof. PharmDr. Emil Rudolf, Ph.D.
• Comes under: General medicine - ELECTIVE subjects
• Pre-requisite : {Malá skupina pro předmět FV111}
• Incompatibility : FG50033
• Interchangeability : FG50033
• Is incompatible with: FG50033
• Is interchangeable with: FG50033

Literature

Compulsory literature:

1. Internet - based on-line databases Medline and PubMed

Last update: Laláková Marcela (06.02.2026)

Requirements to the exam

Credit:

• attendance
• Credit test – three attempts, 75 % passing grade

Last update: Laláková Marcela (06.02.2026)

Syllabus

Lecturers:

• Prof. PharmDr. Emil Rudolf, Ph.D.
• Assoc. prof. Dr. Věra Králová, Ph.D.
• Dr. Stanislav John, Ph.D.

Lectures:

1. Tumor heterogeneity (Rudolf)
2. Stem cell concept in tumorigenesis (Králová)
3. Signaling pathways in tumor cells (Rudolf)
4. Chemoresistance and metabolism in tumor cell (Rudolf)
5. Barriers of tumorigenesis in tumor cells (Rudolf)
6. Invasion and metastasis (Rudolf)
7. Step by step carcinogenesis in selected examples of human malignancies (John)
8. New approaches to biological treatment of tumors (Rudolf)
9. Summary of course I, Credit test (Rudolf, Králová)
10. Summary of course II (Rudolf, Králová)

Last update: Laláková Marcela (06.02.2026)