SubjectsSubjects(version: 983)
Course, academic year 2025/2026
   
Pathobiochemistry and Disorders of Metabolism and Nutrition - FV086
Title: Pathobiochemistry and Disorders of Metabolism and Nutrition
Guaranteed by: Academic Department of Internal Medicine (15-400)
Faculty: Faculty of Medicine in Hradec Králové
Actual: from 2021
Semester: summer
Points: 0
E-Credits: 2
Examination process: summer s.:
Hours per week, examination: summer s.:0/30, C [HS]
Capacity: 25
Min. number of students: 5
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: not taught
Language: English
Teaching methods: full-time
Level:  
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: prof. MUDr. Zdeněk Zadák, CSc.
doc. MUDr. Alena Stoklasová, CSc.
Pre-requisite : {Pathological Physiology II}
Incompatibility : FA0108155
Schedule   
Annotation
The metabolic disorders, their diagnostics and treatment are discussed. Substrates in parenteral and enteral nutrition – their choice and combinations. Treatment of shock, sepsis, multiorgan insufficiency. The discussion is based on the application of knowledge of biochemistry and pathology that allows to improve the understanding of diseases and their adequate treatment.
Last update: Rohlenová Martina, Mgr. (14.08.2019)
Literature
  1. Sobotka L. - editor Basics in Clinical Nutrition, Galen, 2000, 2004, ISBN: 80-7262-070-3
  2. synopsis in MOODLe
Last update: Rohlenová Martina, Mgr. (14.08.2019)
Requirements to the exam

Attendance. Credit test: Multiple choice questionnaire based on discussed topics; a case report.

Last update: Rohlenová Martina, Mgr. (14.08.2019)
Syllabus

Lecturers:

  • prof. MUDr. Vladimír Blaha, CSc.
  • prof. MUDr. Luboš Sobotka, CSc.
  • prof. MUDr. Zdeněk Zadák, CSc.
  • doc. MUDr. Alena Stoklasová, CSc.
  • MUDr. Eduard Havel, Ph.D.
  • MUDr. František Musil, Ph.D.    

Seminars and practical courses:

  1. The applications of biochemical mechanisms in the clinical practice. Dyslipidaemias, their classification, phenotypes, pathophysiology. Management of dyslipidaemias - diet and drug treatment.
  2. Case reports: dyslipidaemias – their treatment.
  3. Malnutrition – metabolic changes. Anorexia mentalis, obesity – their treatment.
  4. Diabetes mellitus - types, sources of energy. Case reports. Treatment and nutrition of a diabetic mellitus.
  5. The assessment of energy sources available in PEN and EN, standard substrates, organ specific substrates.
  6. The utilization of energy sources in critically ill patients. Indirect energometry, the introduction into the methods of metabolism monitoring.
  7. Case reports: the strategy of volume supplement in patients with cardiovascular insufficiency.
  8. Organ specific substrates in treatment of shock, sepsis, multiorgan insufficiency, liver and renal insufficiencies. Water and mineral supplementation.
  9. Management of geriatric patients.
  10. Consultation. Credit test.
Last update: Rohlenová Martina, Mgr. (14.08.2019)
 
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