Pathobiochemistry and Disorders of Metabolism and Nutrition - FG50002

• Title: Pathobiochemistry and Disorders of Metabolism and Nutrition
• Guaranteed by: Academic Department of Internal Medicine (15-400)
• Faculty: Faculty of Medicine in Hradec Králové
• Actual: from 2023
• Semester: summer
• Points: 0
• E-Credits: 2
• Examination process: summer s.:
• Hours per week, examination: summer s.:0/30, C [HS]
• Capacity: 25
• Min. number of students: 5
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: not taught
• Language: English
• Teaching methods: full-time
• Note: course can be enrolled in outside the study plan; enabled for web enrollment
• Guarantor: prof. MUDr. Zdeněk Zadák, CSc.; doc. MUDr. Alena Stoklasová, CSc.
• Pre-requisite : {Pathological Physiology II}
• Incompatibility : FA0108155

Annotation

The metabolic disorders, their diagnostics and treatment are discussed. Substrates in parenteral and enteral nutrition - their choice and combinations. Treatment of shock, sepsis, multiorgan failure. The discussion is based on the application of knowledge of biochemistry and pathology that allows to improve the understanding of diseases and their adequate treatment.

Last update: STOKL/LFHK.CUNI.CZ (02.02.2022)

Literature

Sobotka L. - editor Basics in Clinical Nutrition, Galen, 2000, 2004, ISBN: 80-7262-070-3

handouts in MOODLE

 

Last update: STOKL/LFHK.CUNI.CZ (01.02.2023)

Requirements to the exam

Attendance - two absences are tolerated

Credit test: Multiple choice questionnaire based on discussed topics; a case report.

Last update: STOKL/LFHK.CUNI.CZ (01.02.2023)

Syllabus

Seminars

1. The applications of biochemical mechanisms in the clinical practice. Dyslipidaemias, their classification, phenotypes, pathophysiology. Management of dyslipidaemias - diet and drug treatment.

2. Case reports: dyslipidaemias - their treatment.

3. Malnutrition - metabolic changes. Anorexia mentalis, obesity - their treatment.

4. Diabetes mellitus - types, sources of energy. Case reports. Treatment and nutrition of a diabetic.

5. The assessment of energy sources available in PEN and EN, standard substrates, organ specific substrates.

6 .Case reports: the strategy of volume supplement in patients with cardiovascular insufficiency.

7. Organ specific substrates in treatment of shock, sepsis, multiorgan insuffiency, liver and renal insufficiencies. Water and mineral supplementation.

8. Management of geriatric patients.

9. The utilization of energy sources in crtically ill patients. Indirect energometry, the introduction into the methods of metabolism monitoring.

10. Consultation. Credit test.

Lecturers

Prof. Vladimir Blaha, M.D., Ph.D.

Prof. Luboš Sobotka, M.D., Ph.D.

Prof. Zdeněk Zadák, M.D., Ph.D.

Assoc. Prof. Alena Stoklasová, M.D., Ph.D.

Eduard Havel, M.D., Ph.D.

Fratišek Musil, M.D., Ph.D.

Pavel Skořepa, M.D., Ph.D.

Jakub Víšek, M.D., Ph.D.

 

 

Last update: STOKL/LFHK.CUNI.CZ (01.02.2023)