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Course, academic year 2019/2020
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Histology and Embryology II - EA0103012
Title in English: Histologie a embryologie II
Guaranteed by: Ústav histologie a embryologie (14-40)
Faculty: Faculty of Medicine in Pilsen
Actual: from 2017
Semester: winter
Points: 6
E-Credits: 6
Examination process: winter s.:
Hours per week, examination: winter s.:2/3 C+Ex [hours/week]
Capacity: unlimited / unlimited (unknown)
Min. number of students: unlimited
State of the course: taught
Language: English
Teaching methods: full-time
Level:  
Additional information: http://www.lfp.cuni.cz/histologie/eng_education.html
Note: deregister from the exam date if a requisite was not fulfilled
for a repeated registration for Course credit + Exam, the student must have the Course credit exam passed
Guarantor: prof. MUDr. Milena Králíčková, Ph.D.
Teacher(s): prof. MUDr. Milena Králíčková, Ph.D.
MUDr. Věra Křížková, Ph.D.
MUDr. Anna Malečková
Ing. et Ing. Jiří Polívka, Ph.D.
prof. MUDr. Mgr. Zbyněk Tonar, Ph.D.
Ing. Bc. Lucie Vištejnová, Ph.D.
Classification: Medicine > Basic Sciences
Co-requisite : EA0102001, EA0102004
Is co-requisite for: EA0105021, EA0105085, EA0105084, EA0106014, EA0106113, EA0106013, EA0105022
Annotation -
Last update: prof. MUDr. Mgr. Zbyněk Tonar, Ph.D. (08.11.2017)
Students will learn and understand how to describe the microscopic structure of various organs of human body. In the practical classes, the students will optical microscope for identification and description of histological slides.
Students will learn about the development of human body, starting with formation of gametes, fertilization, through early embryonic development, organogenesis, fetal growth, and finally up to birth. Students will learn about the main phases of development of individual organs and organ systems in order to understand the origin of the most common malformations.
Course completion requirements -
Last update: prof. MUDr. Mgr. Zbyněk Tonar, Ph.D. (08.11.2017)

The winter semester is finished by credit and examination. Acquiring credit for the summer (1st year) and the winter semester is a condition for being admitted to the exam.

Conditions for acquiring the credit for the winter semester:

1. Participation in practical exercises - no more than two classes per semester may be missed

2. Successful passing of the credit test

3. Description of unlabeled histological slides

Conditions for successful passing the exam:

1. Successful passing of the test in the computer room at the Dean's Office of the Faculty of Medicine in Pilsen (Husova 3)

2. Written part - correct drawing and description of four schemes - two from general histology and two from embryology

3. Successful identification of three unlabeled histological slides using a microscope

4. Oral examination consisting of three theoretical questions: one from general histology, one from special histology, and one from embryology

Literature -
Last update: prof. MUDr. Mgr. Zbyněk Tonar, Ph.D. (08.11.2017)

Mandatory reading and textbooks:

•Slípka J.: Outlines of histology. Karolinum 2004

•Slípka J.: Outlines of embryology. Karolinum 2012

•Junqueira L.C., Carneiro J., Kelley R.O.: Basic Histology. LANGE medical book, 2005

•Ovalle W., Nahirney P.: Netter´s Essential Histology, 2nd edition, Elsevier 2013

•Gartner L.P., Hiatt J.L.: Color Atlas and Text of Histology. 6th edition. Wolters Kluwer, 2014

•Ross M., Pawlina W.: Histology: a Text and Atlas with Correlated Cell and Molecular Biology. 6th edition. Wolters Kluwer, 2014

•Young B., Woodford P., O´Dowd G.: Wheater´s Functional Histology. A text and colour atlas. 6th edition, Churchill Livingstone, 2013

•Sadler T.: Langman´s Medical Embryology, 13th edition, Wolters Kluwer 2014

•Moore K.L., Persaud T.V.N., Torchia M.G.: Before We Are Born, 9th Edition. Elsevier, Philadelphia, 2016

•Moore K.L., Persaud T.V.N., Torchia M.G.: The Developing Human, 10th Edition. Clinically Oriented Embryology. Elsevier, Philadelphia, 2016

 

Recommended reading and textbooks:

•Matsumura G., England M. A.: Embryology colouring book. Mosby (An imprint of Harcourt Publishers Ltd.), 1999

•Christ B., Wachtler F.: Medizinische embryologie. Ullstein Medical Verlagsgesellschaft, Wiesbaden, 1998

•Ovalle W., Nahirney P.: Netter´s Histology Flash Card Updated Edition, 1st edition, Elsevier 2013

•Lee L.: Lippincott's Pocket Histology. Wolters Kluwer, 2014

•Lowe J.S., Anderson P.G. Human Histology, 4th Edition. Elsevier, Philadelphia, 2015

•Berkovitz, B.K.B. – Holand, G.R.: Colour Atlas and Textbook of Oral Anatomy,Histology and Embryology 3rd Edition, Elsevier Science 2005

•Cochard L.: Netter´s Atlas of Human Embryology, 1st edition, Saunders Elsevier 2012

•Carlson B.M.:Human Embryology and Developmental Biology, 5th edition, Saunders Elsevier 2013

Requirements to the exam -
Last update: Ing. Jiřina Havránková (24.05.2018)

The winter semester is finished by credit and examination. Acquiring credit for the summer (1st year) and the winter semester is a condition for being admitted to the exam.

Conditions for acquiring the credit for the winter semester:

1. Participation in practical exercises - no more than two classes per semester may be missed

2. Successful passing of the credit test

3. Description of unlabeled histological slides

Conditions for successful passing the exam:

1. Successful passing of the test in the computer room at the Dean's Office of the Faculty of Medicine in Pilsen (Husova 3)

2. Written part - correct drawing and description of four schemes - two from general histology and two from embryology

3. Successful identification of three unlabeled histological slides using a microscope

4. Oral examination consisting of three theoretical questions: one from general histology, one from special histology, and one from embryology

Syllabus -
Last update: prof. MUDr. Mgr. Zbyněk Tonar, Ph.D. (08.11.2017)

Summary of the lectures - Embryology. General medicine 2nd year:

1. INTRODUCTION: Embryological terms. The ethical problems of Embryology. History of embryology. Blastogenesis. Fertilization and differentiation. Cleavage.

2. BLASTOGENESIS and GASTRULATION: Blastocyst, Implantation, Gastrulation. Origin of the first Germ layers. Notogenesis (development of notochord). The

embryonic disc and its development. Mesoderm and development of somites. Mesenchyme.

3. FETAL MEMBRANES AND PLACENTA DEVELOPMENT: Amniotic sac expansion. Rotation of embryo. Amnion. Chorion. Placenta. Embryonic and fetal growth. Marks of the fetal maturity. Delivery.

4. NERVOUS SYSTEM DEVELOPMENT: Neural plate, groove and tube. Brain vesicles. Development of sense organs. The eye and inner ear.

5. CIRCULATORY SYSTEM DEVELOPMENT I.: First embryonic and extraembryonic circulation. Development of major vessels. Aortal arches. Veins.

6. CIRCULATORY SYSTEM. DEVELOPMENT II.: Heart loop. Septation of the atria and ventricles. Common cardial malformations.

7. DIGESTIVE SYSTEM DEVELOPMENT I.: Delimitation of the yolk sac.

Archenteron. Stomodeum. Branchial region. Teeth. Derivatives of the branchial clefts, pouches and arches. Development of Tongue.

8. DIGESTIVE and RESPIRATORY SYSTEM DEVELOPMENT: Rotation of Intestine. Liver, Pancreas and Spleen Development. Respiratory passages and Lung Development.

9. URINARY SYSTEM DEVELOPMENT: Pronephros. Mesonephros. Metanephros. Urinary passages. Cloaca.

10. GENITAL SYSTEM DEVELOPMENT: Gonade. Wolffian and Müllerian ducts. External genital organs.

11. OROFACIAL REGION, SKULL and SKELETAL DEVELOPMENT: Nose. Olfactory organ.Upper and lower jaws development. Development of the secondary Palate.

Cleft malformations. Axial skeleton. Extremities. Skull. Muscles and Skin Development.

 

Summary of the practical sessions. Systematic histology. General medicine 2nd year:

1. Introduction: Revision. The rules of health security during the teaching process of Histology.

2. Digestive system I.: Oral cavity - Tongue (radix and dorsum liguae), Soft palate, Lip, Tooth development.

3. Digestive system II.: Oesophagus, Stomach, Duodenum, Small intestine, Colon, Appendix vermiformis.

4. Digestive system III.: Liver, Gall bladder, Salivary glands, Pancreas.

5. Respiratory system: Epiglottis, Trachea, Lung.

6. The TEST.

Urinary system: Kidney, Ureter, Urinary bladder.

7. Male reproductive system: Testis, Epididymis, Prostate, Spermatic cord, Scrotum.

8. Female reproductive system I.: Ovary, Uterine tube, Uterus.

9. Female reproductive system II.: Pregnant uterus, Placenta, Umbilical cord, Vagina, Labia minora & majora.

10. Circulatory and lymphatic system: Myocard, Aorta, Femoral artery, Artery and Vein of the lower extremity, Vessels of various organs, Capillaries. Lymph node,

Tonsils, Spleen, Thymus. Revision.

11. Endocrine system: Hypophysis, Suprarenal gland, Thyroid gland, Pancreas.

12. The TEST.

Skin: Thick and thin type - Planta pedis, Axilla, Palpebra, Pinna, Mammary gland (inactive and lactating).

13. Nervous system: Spinal cord, Cerebellum, Cerebral cortex, Peripheral nerve, Myelin sheath, Sensitive nerve endings. Sensory organs demonstration.

14. Revision of the whole topic. Tooth development. Examination. COURSE CREDIT.

Course completion requirements -
Last update: prof. MUDr. Mgr. Zbyněk Tonar, Ph.D. (08.11.2017)

The winter semester is finished by credit and examination. Acquiring credit for the summer (1st year) and the winter semester is a condition for being admitted to the exam.

Conditions for acquiring the credit for the winter semester:

1. Participation in practical exercises - no more than two classes per semester may be missed

2. Successful passing of the credit test

3. Description of unlabeled histological slides

Conditions for successful passing the exam:

1. Successful passing of the test in the computer room at the Dean's Office of the Faculty of Medicine in Pilsen (Husova 3)

2. Written part - correct drawing and description of four schemes - two from general histology and two from embryology

3. Successful identification of three unlabeled histological slides using a microscope

4. Oral examination consisting of three theoretical questions: one from general histology, one from special histology, and one from embryology

 
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