The subject Infection and tropical medicine is addressed to students of general medicine, 5th year. Students learn pathogenesis, clinical presentation, diagnostics, differential diagnosis and principles of therapy of infectious diseases. The spectrum of diseases follows the actual needs of the subject in the Czech Republic.
The primary goal is to teach students to diferentiate infectious diseases, to diagnose them and adopt the principles of treatment.
The secondary goal is to understand relations between microorganisms and human beeings, to be aware of the global aspect of infectious diseases, to understand the specific position of antibiotic (antiinfection) therapy among other therapeutic modalities.
Jirina Hobstova (ed.): Infectious Diseases. 2nd edition. Charles University in Prague, Karolinum Press 2012
seminars, bedside training
80% attendance at the lessons (minimum 7 days out of the total 8 days, attendance at both the seminars and bedside practice) is required for credit. Upon late arrival beyond 15 minut the attendance will not be recorded. The Credit will be given at the end of the course supposed that the required attendance was fulfilled. Without getting the Credit the student cannot sign up for the exam.
Questions for exam in Infection and geographic medicine, General medicine, 5th year
Part I: Organ-oriented approach and special situations
1. Acute tonsillopharyngitis (sore throat) syndrome
2. Acute epiglottitis, laryngitis and laryngotracheitis
3. Community-acquired pneumonia
4. Purulent meningitis (incl. neonatal age)
5. Aseptic meningitis and encephalitis
6. Acute diarrhoea
7. Skin and musculoskeletal infections of bacterial origin
8. Infectious diseases with maculopapular exanthem
9. Infectious diseases with vesicular and pustular exanthem
10. General overview of liver infections. Parenchymatic infections diffuse and focal, hepatobiliary infections
11. Upper and lower urinary tract infections
12. Infective endocardititis
13. Lymphadenopathy and lymfatic tissue infections
14. Sepsis, septic shock
15. Fever of unknown origin. Diagnostic approach, common causes in temperate climatic zones.
16. Fever in patient returning from tropics
17. Diarrhoea in patient returning from tropics
18. Infectious diseases during pregnancy. Congenital and perinatal infections.
19. Biological weapons, with emphasis on anthrax.
20. Animal bite infections (lyssa, cat-scratch disease).
21. Hospital-acquired infections.
Part II : Pathogen-oriented approach
2. Arboviral infections (tick-borne encephalitis, dengue fever, yellow fever)
3. Epidemic parotitis and enteroviral infections (Coxsackie, ECHO viruses, polioviruses)
4. HSV and VZV infections
5. EBV and CMV infections
6. HIV infection. Routes of infection, classification, clinics, diagnosis, therapy, prognosis.
7. Opportunistic infections in HIV disease. Clinics, diagnosis, therapy, prophylaxis
8. Viral hepatitis A-E
9. Staphylococcal infections. Toxic shock syndrome
10. Streptococcal infections. Toxic shock syndrome
11. Pneumococcal infections
12. Meningococcal invasive disease (incl. pathogenesis)
13. Salmonellosis and campylobacteriosis
14. Shigella and E.coli diarhoea infections
15. Spirochetal infections (esp. Lyme borreliosis, leptospirosis)
16. Chlamydia and Mycoplasma infections
17. Clostridial toxin-mediated diseases (esp. botulism, tetanus)
18. Fungal infections in immunocompetent and immunocompromised patients
19. Amoebiasis, giardiasis
21. Intestinal helminthiases (intestinal nematodes, cestodes)
Part III: Antiinfective therapy
1. Beta-lactam antibiotics. Subgroups, antibacterial spectra, indications, adverse effects, mechanisms of resistance.
2. Penicillins. Drugs, antibacterial spectra, indications, doses, adverse effects.
3. Cephalosporins. Drugs, antibacterial spectra, indications, adverse effects.
4. Macrolides, lincosamides. Drugs, antibacterial spectra, indications, adverse effects.
5. Tetracyclines, chloramphenicol, metronidazol. Drugs, antibacterial spectra, indications, adverse effects.
6. Aminoglycosides and glycopeptides. Drugs, antibacterial spectra, indications, adverse effects. Monitoring of therapy.
7. Fluoroquinolones and cotrimoxazol. Drugs, antibacterial spectra, indications, adverse effects.
8. Antibiotic therapy of Gram-positive infections
9. Antibiotic therapy of Gram-negative infections
10. Antibiotic therapy of anaerobic infections
11. Antibiotic therapy of nosocomial infections (resistant bacteria)
12. Chemotherapy of fungal infections. Drugs, indications
13. Chemotherapy of viral infections. Indications, drugs
14. Hyperimmune specific immunoglobulins as part of complex therapy of infections
15. Physiological human microbial flora and its changes due to antibiotics (incl. antibiotic - associated colitis).
Therapy of viral infections. Influenza.
Congenital and perinatal infections
Imported and parasitic infections
Strategy and tactics of antibiotic therapy
Infectious diseases on slides (Exanthema inf., inf. eliminated by vaccination)