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Course, academic year 2017/2018
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Cellular Basis of Medicine - credit summer semestr - CVSE1M0003
Title: Buněčné základy medicíny - zápočet letní semestr
Guaranteed by: Department of Biochemistry, Cell and Molecular Biology 3FM CU (12-BIOC)
Faculty: Third Faculty of Medicine
Actual: from 2017 to 2017
Semester: summer
Points: 10
E-Credits: 10
Examination process: summer s.:
Hours per week, examination: summer s.:154/82, C [HS]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: Czech, English
Teaching methods: full-time
Teaching methods: full-time
Level:  
Guarantor: doc. MUDr. Jan Trnka, Ph.D.
Is pre-requisite for: CVSE1M0001
Examination dates   Schedule   
Annotation -
Last update: Mgr. Vladimíra Kvasnicová (27.09.2018)
Module Cellular Basis of Medicine ("module Cell") consists of four courses - two in the winter semester and two in the summer semester:
 Course 1 - Cell structure and heredity (8 weeks), Course 2 - Cell metabolism and specialisation (7 weeks), Course 3 - Cell signalling and immunity (7 weeks), Course 4 - Cell cycle and development (8 weeks). The teaching in this module is carried out by the Department of biochemistry, cell and molecular biology, Department of histology and embryology, Department of medical genetics and Department of immunology.
Aim of the course -
Last update: prof. RNDr. Eva Samcová, CSc. (30.11.2011)

The aim of the subject should be to submit self-contained knowledge about cells and tissues. The  students obtain basic knowledge in molecular biology, biochemistry, histology, genetics and imunology by integrated form of teaching.

Literature -
Last update: Mgr. Vladimíra Kvasnicová (26.09.2019)

MOLECULAR BIOLOGY

  • Alberts B. et al.: Essential Cell Biology. Garland Science, New York & London, 2010
  • Alberts B. et.al.: Molecular Biology of the Cell. Garland Science, New York, 2008 
  • Lodish H. et al.: Molecular Cell Biology. W. H. Freeman and Company, New York, 2008
  • Knowles M. and Selby P.: Introduction to the Cellular and Molecular Biology of Cancer. Oxford University Press, Oxford & New York, 2005

 BIOCHEMISTRY

  • Rodwell Victor W.: Harper´s Illustrated Biochemistry, 31st ed., 2018, ISBN 978-1259837937 (main recommended textbook for biochemistry)
  • Jan Koolman, Klaus-Heinrich Röhm: Color Atlas of Biochemistry, Thieme, Stuttgard, 2012, ISBN 978-3131003737, also available from http://www.lf3.cuni.cz/en/departments/svi/e-book/foreign-books/index.html  
  • Pamela C. Champe, Richard A. Harvey: Lippincott´s Illustrated Reviews - Biochemistry, ISBN 0-397-51091-8
  • Thomas M. Devlin et al.: Textbook of Biochemistry With Clinical Correlations, 4th ed., ISBN 0-471-15451-2

 GENETICS

  • Robert L. Nussbaum, Roderick R. McInnes, Huntington F. Willard: Thompson and Thompson: Genetics in Medicine. Eighth edition, Elsevier 2016, ISBN 978-1-4377-0696-3
  • Lynn B. Jorde, John C. Carey, Michael J. Bamshad: Medical Genetics. Fifth edition, Elsevier 2016, ISBN 978-0-323-18835-7
  • Dorian J. Pritchard, Bruce R. Korf: Medical Genetics at a Glance. Second edition, Blackwell Publishing 2008

 HISTOLOGY

  • Junqueira LC, Carneiro J: Basic Histology. Text and atlas. 14th ed. (last one) McGraw-Hill, New York 2005.
  • Ross and Pawlina: Histology - a Text and Atlas (with correlated cell and  molecular biology)
  • Young B, Heath JW: Wheather's Functional Histology: a Text and Colour Atlas. 5th ed. Churchill Livingstone, Edinburgh 1993.
  • Kierszenbaum AL: Histology and Cell Biology. An Introduction to Pathology. Mosby Elsevier, Philadelphia
  • Eroschenko VP.: diFiore´s Atlas of Histology with functional correlations – my opinion : a bit simplified , but a lot of good pictures
  • Kerr JB: Functional Histology, 2nd ed, Mosby, 2010.
  • Moore KL,Persaud TVN: The Developing Human: Clinically Oriented Embryolog, 10 th ed,  Elsevier, 2015,  ISBN 80-85866-94-3
  • Sadler TW:  Langman´s Medical Embryology, 13 th  ed., William and Wilkins 2015, ISBN-13: 978-1451191646

 IMMUNOLOGY

  • Abbas, AH Lichtman, S Pillai.  Cellular and Molecular Immunology, Elsevier, 2011. 7th ed.
  • Roitt I, Delves PJ: Essential Immunology. Blackwell Scientific Publications 2012, 12th ed.
  • Kindt TJ: Kuby Immunology, New York : W.H. Freeman, 2006 
  • Immunobiology, Janeway CA et al., available at: http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=imm.TOC&depth=2
  • Any other immunology textbook can be used
Teaching methods -
Last update: prof. RNDr. Eva Samcová, CSc. (30.11.2011)

Forms of teaching in this module include lectures, seminars and practicals.
Essay topics are assigned by teachers before some seminars in which they are to be presented by students.

Requirements to the exam -
Last update: Mgr. Vladimíra Kvasnicová (27.09.2020)

Requirements for semestral credits

- rules for winter and summer semesters are the same:

1) participation in practicals

2) presentation of essays

3) tests

 

Requirements for fulfilment of credit conditions and rules for their substitution


1) practicals
: active participation and knowledge are assessed, a laboratory coat is required

  • biochemical practicals - processing of given tasks, laboratory reports
  • histological slides - worked-out workbook, test on slides
  • molecular biology practicals - processing of given tasks, written test
  • cytogenetics practicals - processing of given tasks

rules for substitution of practicals:

  • there are compensatory dates of practicals; written elaboration of missing task and testing is possible only in case of proved relevant reasons of absence (e.g. illness)

  

2) essays: essay content and oral presentation are assessed

  • clinical detective stories 1 - 9 - preparation in advance, active participation at seminars (= presentation and discussion)
  • seminar paper on inherited disorder (once in the academic year) - presentation at a seminar from genetics
  • seminar presentation on substances essential for development (once in the summer semester) - presentation at a seminar from biochemistry

rules for substitution of essays:

  • written elaboration needs to be personally hand in and presented to your teacher

 

3) semestral credit tests: performance in the tests is assessed

  • each semestral test is divided into two course tests taken after each course during both semesters (i.e. 2 tests in the winter and 2 tests in the summer semester), you have 70 min. for the test; credit tests include both the TRUE/FALSE questions and Short Answer questions, you need to obtain at least 5 from 10 points each semester, the points are added to your exam result
  • if you do not perform adequately in the course tests you has to take the combined test from both courses of the semester at once (i.e. winter combined test and/or summer combined test), you have 90 min. for the test; the combined test include only TRUE/FALSE questions, you need at least 70% of points from the test, the points are NOT added to your exam results
  • you must be sign up in the SIS for the combined tests

rules for substitution of tests:

  • there are three dates of combined tests (the winter combined test can be taken 1x in February, 1x in June and 1x in September; the summer combined test can be taken 2x in June and 1x in September; you must be sign up in the SIS for the combined tests; CAUTION: the combined tests in June are held after the first exam test (= pre-term) date

 

For more information see the application Vyuka  (http://vyuka.lf3.cuni.cz/)

In case of questions regarding the module use cell@lf3.cuni.cz

Syllabus -
Last update: Mgr. Vladimíra Kvasnicová (27.09.2018)

Detailed information about lectures, seminars and practicals are available at http://vyuka.lf3.cuni.cz/

Courses of the winter semester                                                                                                                                                

  • Course 1  -  Cell structure and heredity
  • Course 2  -  Cell metabolism and specialisation                                                                                                                                                                 

Courses of the summer semester                                                                                                                                                 

  • Course 3 - Cell signalling and immunity                                                                 
  • Course 4 - Cell cycle and development             
Entry requirements -
Last update: prof. RNDr. Eva Samcová, CSc. (08.12.2011)

Biology and chemistry knowledge on the secondary school level.

 
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