SubjectsSubjects(version: 901)
Course, academic year 2022/2023
  
Biomedicine and Biotechnology - B90275
Title: Biomedicine and Biotechnology
Guaranteed by: BIOCEV, First Faculty of Medicine, Charles University (11-00131)
Faculty: First Faculty of Medicine
Actual: from 2019
Semester: summer
Points: 0
E-Credits: 0
Examination process: summer s.:
Hours per week, examination: summer s.:0/0 C [hours/week]
Capacity: unlimited
Min. number of students: unlimited
Virtual mobility / capacity: no
State of the course: taught
Language: English
Teaching methods: full-time
Note: course is intended for doctoral students only
Guarantor: prof. MUDr. Tomáš Stopka, Ph.D.
Annotation
Last update: Mgr. Martina Renková (27.01.2020)
This subject focuses on educating students in biomedical research and biotechnologies. It teaches the basis of scientific work, introduction to methodology in biomedicine up to the development of novel diagnostics and therapeutics. Lectures and seminars will contain the insight into modern tools such as transgenic biology or global technologies such as OMICs. Students are encouraged to read education material (available at https://biocev.lf1.cuni.cz/vyuka) ahead of the seminar. Presentation of selected education material, which constists a research publication, will be included in the final seminar day.
Teaching methods
Last update: Ing. Lucie Vyšatová (05.04.2022)

Annotation: This subject focuses on educating students in biomedical research and biotechnologies. It teaches the basis of scientific work, introduction to methodology in biomedicine up to the development of novel diagnostics and therapeutics. Lectures and seminars will contain the insight into modern tools such as transgenic biology or global technologies such as OMICs.

Summer Term (ACADEMIC YEAR 2021/2022)

Lectures will be held in BIOCEV (Conference Hall U2.012 or Seminary Room U2.020, Průmyslová 595, 252 50 Vestec) every second week starting from March 3rd, 2022, from 4 PM. Students are encouraged to read education material listed below ahead of the seminar. In case of questions, please do not hesitate to contact Lucie Vyšatová (lucie.vysatova@lf1.cuni.cz, +420 325 873 031)

Lecture 1: 3.3. 2022

Prof. MUDr. Karel Smetana, DrSc.

Title: CELL BIOLOGY Tumor ecosystem - Role of cancer microenvironment in the control of tumor biology including metastazation. Cancer-associated fibroblasts.

Study material: [PDF1] [PDF2] [PDF3]

Lecture 2: 17.3. 2022 

RNDr. Radoslav Janoštiak, Ph.D.

Title: Biology of solid tumors and translational medicine

Basic principles of cancer development, cancer driver mutations and targeted therapy, cancer evolution and progression, cancer cell dormancy and invasiveness, circulating tumor cells.

Study material: [PDF1] [PDF2] [PDF3] [PDF4]

Lecture 3: 31.3. 2022

Prof. MUDr. Tomáš Stopka, Ph.D.

Title: CELL BIOLOGY II: Stem cell biology versus proliferation and differentiation control

Regulatory mechanisms in normal cell differentiation including transcription factors and their effector pathways. Biology of stem cells and tissue transplantation. Regulation of cell cycle and its detection.

Study material: [PDF1][PDF2][PDF3][PDF4][PDF5][PDF6]

Lecture 4: 21.4. 2022 

Mgr. Miroslav Hons, PhD

Title: LEUKOCYTE MIGRATION AND IMMUNOLOGY

Migration of leukocytes in healthy and pathological states. Imaging of leukocyte behaviour and interactions. Cell biology of leukocyte motility.

Study material: [PDF1][PDF2][PDF3]

Lecture 5: 28.4. 2022

MUDr. Ondřej Havránek, PhD

TitleGENETICS : Cancer genomes and genome editing technology
Cancer associated acquired DNA mutations and their role in tumor development, progression, and therapy resistance. Consequences for interaction of tumor cells with immune system. Use of genome modifying technologies to create models for cancer research and options for therapy.

Study material: [PDF1][PDF2][PDF3][PDF4][PDF5][PDF6][PDF7][PDF8][PDF9][PDF10]

Lecture 6: 12.5. 2022

Mgr. Peter Dráber, PhD

TitleThe role of cell death in tissue homeostasis and autoimmune disorders
Cell death is necessary for removal of damaged cells and tissue renewal. However, aberrant cell death can lead to severe autoimmune disorders. The molecular pathways triggering cell death in physiological settings and pathological conditions will be discussed.

Study material: [PDF1][PDF2][PDF3]

Lecture 7: 26.5. 2022

Assoc.Prof. RNDr. Jiří Petrák, Ph.D.

Title: CLINICAL PROTEOMICS

Using efficient separation methods and high-resolution mass spectrometry PROTEOMICS enables monitoring of quantitative and qualitative changes of thousands of proteins in biological samples. Detailed knowledge of proteome changes in cells and tissues can elucidate molecular mechanisms of physiologic and pathologic processes, and identify disease markers or novel therapeutic targets.

Study material: [PDF1][PDF2]

 

Registration requirements - Czech
Last update: Ing. Lucie Vyšatová (25.01.2021)

Starting on Thursday March 4th, 2021 on bi-weekly basis.

Furhter information can be found at: https://biocev.lf1.cuni.cz/vyuka
Registration: send an email to Ing. Lucie Vysatova: lucie.vysatova@lf1.cuni.cz

 
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