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Immunology in Dentistry - B81144 (Dentistry)

Title:	Immunology in Dentistry
Guaranteed by:	Institute of Clinical Immunology and Allergology First Faculty of Medicine and General University Hospital (11-00352)
Faculty:	First Faculty of Medicine
Actual:	from 2024
Semester:	summer
Points:	3
E-Credits:	3
Examination process:	summer s.:
Hours per week, examination:	summer s.:1/0, C [HT]
Extent per academic year:	15 [hours]
Capacity:	unlimited
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
State of the course:	taught
Language:	English
Teaching methods:	full-time
Explanation:	MUDr. Mgr. Jitka Petanová, CSc., jitka.petanova@lf1.cuni.cz

Guarantor:	prof. MUDr. Ilja Stříž, CSc.
Attributes:	Teoretický předmět Zubní lékařství
Pre-requisite :	{splněna jedna z anatomií}, B81129, B83031
Is pre-requisite for:	B81407, B81162

Opinion survey results Noticeboard

Annotation -

The role of the immune system during the disease of the oral cavity with respect to mucosal immunity. The importance of the oral tolerance to keep the oral health. Reactions to dental materials used in stomatology.

Last update: Petanová Jitka, MUDr. Mgr., CSc. (21.02.2019)

Aim of the course

basic immunologic mechanisms and their function in the development of the oral cavity diseases

Last update: Petanová Jitka, MUDr. Mgr., CSc. (30.09.2019)

Course completion requirements

credit test - min. 17 points (max. 20)

To receive credits from Immunology in dentistry, you have to pass through credit test (Department of Stomatology, Karlovo nam. 32, building A, 5th floor - small lecture hall)

Last update: Petanová Jitka, MUDr. Mgr., CSc. (12.02.2024)

Literature -

LAMONT R.J., BURNE´R.A., LANTZ M.S., LEBLANC D. eds.: Oral microbiology and immunology ASM Press Washington DC, 2006
Městecký J., editor. Mucosal Immunology. 4th edition Elsevier Academic Press, 2015

Podzimek S, Mysak J, Janatova T, Duskova J. C-Reactive Protein in Peripheral Blood of Patients with Chronic and Aggressive Periodontitis, Gingivitis, and Gingival Recessions. Mediators of Inflammation. 2015;2015:564858. doi:10.1155/2015/564858.

Bartova J, Sommerova P, Lyuya-Mi Y, et al. Periodontitis as a Risk Factor of Atherosclerosis. Journal of Immunology Research. 2014;2014:636893. doi:10.1155/2014/636893.

Mysak J, Podzimek S, Sommerova P, et al. Porphyromonas gingivalis: Major Periodontopathic Pathogen Overview. Journal of Immunology Research. 2014;2014:476068. doi:10.1155/2014/476068.

Borilova Linhartova P, Kastovsky J, Lucanova S, et al. Interleukin-17A Gene Variability in Patients with Type 1 Diabetes Mellitus and Chronic Periodontitis: Its Correlation with IL-17 Levels and the Occurrence of Periodontopathic Bacteria. Mediators of Inflammation. 2016;2016:2979846. doi:10.1155/2016/2979846.

Bartova J, Borilova Linhartova P, Podzimek S, et al. The Effect of IL-4 Gene Polymorphisms on Cytokine Production in Patients with Chronic Periodontitis and in Healthy Controls. Mediators of Inflammation. 2014;2014:185757. doi:10.1155/2014/185757.

Borilova Linhartova P et al. Apolipoprotein E gene polymorphisms in relation to chronic periodontitis, periodontopathic bacteria, and lipid levels. Arch Oral Biol 2015 Mar;60(3):456-62. doi: 10.1016/j.archoralbio.2014.10.003. Epub 2014 Oct 26.

Last update: Petanová Jitka, MUDr. Mgr., CSc. (30.09.2019)

Teaching methods

In person lectures - Department of Stomatology, Karlovo nam. 32, building A, 5th floor - small lecture hall

Last update: Petanová Jitka, MUDr. Mgr., CSc. (12.02.2024)

Requirements to the exam

credit - attendance at lectures recommended, credit test (min. 75% points)

To receive credits from Immunology in dentistry, you have to pass through credit test.

Last update: Petanová Jitka, MUDr. Mgr., CSc. (06.02.2026)

Syllabus -

Oral cavity and mucosal immunology
Oral cavity diseases. Oral manifestations of systemic diseases.
Dental materials and pigmentations
Galvanism and metal intolerance diagnostics
MELISA test + case studies

Last update: Petanová Jitka, MUDr. Mgr., CSc. (21.02.2019)

Entry requirements

prerequisities

Last update: Petanová Jitka, MUDr. Mgr., CSc. (12.02.2024)

Registration requirements

prerequisities

Last update: Petanová Jitka, MUDr. Mgr., CSc. (12.02.2024)

Education plan -

Schedule semestral
Educational week	Date	From - To	Education type	Theme	Teacher	Files	Note	Hodnocení
2	05.03.2026	14:15 - 15:45	lecture	Oral cavity diseases I. - dental caries, periodontal diseases, oral mucosa diseases	RNDr. Štěpán Podzimek, Ph.D.		Department of Stomatology, Karlovo nam. 32, 5th floor - small lecture hall.
4	19.03.2026	14:15 - 15:45	lecture	Oral cavity diseases II. - dental caries, periodontal diseases, oral mucosa diseases	RNDr. Štěpán Podzimek, Ph.D.
6	02.04.2026	14:15 - 15:45	lecture	Holiday
8	16.04.2026	14:15 - 15:45	lecture	Dental materials, pigmentations.	RNDr. Štěpán Podzimek, Ph.D.
10	30.04.2026	14:15 - 15:45	lecture	Galvanism and metal intolerance diagnostics	RNDr. Štěpán Podzimek, Ph.D.
12	14.05.2026	14:15 - 15:45	lecture	Oral manifestations of systemic diseases.	RNDr. Štěpán Podzimek, Ph.D.
14	28.05.2026	14:15 - 15:45	lecture+seminar	Summary, Credit test.	RNDr. Štěpán Podzimek, Ph.D.