Cell biology, basis of genetics, cytogenics, molecular basis of inheritance, basis of immunology and immunogenetics, cell signaling, ontogenesis, carcinogenesis, phylogenesis
Literature
Last update: Bc. Alena Dimitriou (12.09.2023)
Literature for Biology I. + II.
• Your notes from lectures and practical classes and presentations and other materials from classes archived in MS Teams.
• Pritchard DJ and Korf BR. Medical Genetics at a Glance. Wiley-Blackwell, 2013.
• Passarge E. Color Atlas of Genetics. Thieme Verlag, 2017.
• Tobias ES, Connor M and Ferguson-Smith M. Essential Medical Genetics, Wiley, 2011.
Syllabus
Last update: Jan Kovář (01.07.2022)
MEDICAL BIOLOGY II.
second year, winter term
Ecology and ecogenetics 1
principles of ecology, interspecific relationships, parasitism
Ecology and ecogenetics 2
environmental and genetic polymorphism ecogenetics and pharmacogenetics molecular taxonomy and molecular epidemiology
Human molecular genetics 1
structure and organisation of the human genome
Human molecular genetics 2
variability and expression of the human genome
Human molecular genetics 3
molecular basis of human hereditary diseases
Human molecular genetics 4
methods used to study the human genome and in diagnostics problems of modern human genetics
Immunogenetics
innate, adaptive mechanisms, cellular and humoral immune response, phases of immun. response, blood groups and HLA antigenes, immunoglobulins, structure, combinatory diversification, alelic exclusion, alternative splicing
Cell signalling
types of signalling, receptors, ligands, signalling mediated by G protein, secondary messengers
Carcinogenesis 1
malignant cells, antitumor mechanisms, tumor types, monoclonal theory, mutagenesis, cancerogenesis, multistep and multifactorial theory, invasivity, metastatic proces
Carcinogenesis 2
cell proliferation, regulation, proto and oncogenes, tumor supresor genes, oncogenic viruses hereditary malignancies
Evolution 1
molecular and prebiotic evolution, evolutionary theories genetic background of evolutionary processes