Thesis (Selection of subject)Thesis (Selection of subject)(version: 385)
Thesis details
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Bifunctional reagents for selective bioconjugation
Thesis title in Czech: Bifunkční činidla pro selektivní biokonjugace
Thesis title in English: Bifunctional reagents for selective bioconjugation
Key words: biokonjugace, modifikace proteinů, PSI-reagent, serin-selektivní
English key words: bioconjugation, protein modification, PSI-reagent, serine-selective
Academic year of topic announcement: 2023/2024
Thesis type: diploma thesis
Thesis language: angličtina
Department: Department of Organic Chemistry (31-270)
Supervisor: Ing. Ondřej Baszczyňski, Ph.D.
Author: Bc. Kristýna Kellovská - assigned and confirmed by the Study Dept.
Date of registration: 17.10.2023
Date of assignment: 17.10.2023
Confirmed by Study dept. on: 18.01.2024
Date of electronic submission:16.05.2025
Opponents: doc. RNDr. Tomáš Slanina, Ph.D.
 
 
 
Advisors: Ing. Rafael Navrátil, Ph.D.
Guidelines
Předměty z oboru medicinální chemie. Konzultace se školitelem.
References
Veškerá dostupná literatura z databází WOS, Scifinder, Reaxys. Literatura prestižních časopisů Nature, Science, JACS, J. Med. CHem., ACS Infectious dieases, JOC, apod.
Preliminary scope of work
Náplní práce bude návrh, příprava a optimalizace spojek vhodných pro konjugace serinu s dalšími vybranými aminokyselinami. Dále pak studium odborné literatury a všeobecné vzdělávání se v oboru medicinální chemie.
Preliminary scope of work in English
Design, synthesis and optimization of linkers suitable for site-selective bioconjugation of serine with selected aminoacids.
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download fileText of the thesis (defended)3575 kBBc. Kristýna KellovskáBc. Kristýna Kellovská16.05.2025 19:40
 
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