Štúdium mechanizmov prežívania Sertoliho buniek v xenogénnom organizme

• Thesis title in thesis language (Slovak): Štúdium mechanizmov prežívania Sertoliho buniek v xenogénnom organizme
• Thesis title in Czech: Studium mechanizmů přežívání Sertoliho buněk v xenogenním organizmu
• Thesis title in English: Study of mechanisms of Sertoli cell survival in xenogeneic organism
• Key words: Sertoliho buňky, xenogenní transplantace, neonatální tolerance, imunitní odpověď
• English key words: Sertoli cells, xenogeneic transplantation, neonatal tolerance, immune response
• Academic year of topic announcement: 2016/2017
• Thesis type: diploma thesis
• Thesis language: slovenština
• Department: Department of Cell Biology (31-151)
• Supervisor: doc. RNDr. Magdaléna Krulová, Ph.D.
• Author: hidden - assigned by the advisor
• Date of registration: 11.11.2016
• Date of assignment: 15.11.2016
• Date of electronic submission: 13.08.2018
• Date of proceeded defence: 13.09.2018
• Opponents: RNDr. Ladislav Anděra, CSc.

Preliminary scope of work

Cieľom práce je sledovanie prežívania a migrácie prekurzorov Sertoliho buniek v recipientných myšiach. Projekt využíva fenomén neonatálnej tolerancie a evolučne vziadelný donorový organizmus, Xenopus tropicalis, za účelom sledovania konzervovaných mechanizmov modulácie IS pomocou Sertoliho buniek..

Preliminary scope of work in English

The aim of this thesis is to study the survival and migration of SCs precursors in mice recipients. The project is employing the neonatal tolerance phenomenon and evolutionary distinct donor organism, Xenopus tropicalis, to monitor conserved mechanisms of IS modulation usinf SCs.