Zmeny v neurogliách u degeneratívnych porúch centrálneho nervového systému

• Thesis title in thesis language (Slovak): Zmeny v neurogliách u degeneratívnych porúch centrálneho nervového systému
• Thesis title in Czech: Změny v neurogliích u degenerativních poruch centrálního nervového systému
• Thesis title in English: Changes in neuroglia in degenerative disorders of the central nervous system
• Key words: Neurodegenerácia; neuroglie; astrocyty; oligodendrocyty; mikroglie; NG2 bunky; neurodegeneratívne choroby; centrálny nervový systém
• English key words: Neurodegeneration; neuroglia; astrocytes; oligodendrocytes; microglia; NG2 cells; neurodegenerative diseases; central nervous system
• Academic year of topic announcement: 2013/2014
• Thesis type: Bachelor's thesis
• Thesis language: slovenština
• Department: Department of Physiology (31-152)
• Supervisor: prof. MUDr. Petr Zach, CSc.
• Author: hidden - assigned by the advisor
• Date of registration: 11.11.2013
• Date of assignment: 19.12.2013
• Date of electronic submission: 13.05.2014
• Date of proceeded defence: 10.06.2014
• Opponents: Mgr. Miroslav Hock, Ph.D.
• Advisors: doc. RNDr. Jiří Novotný, DSc.

Preliminary scope of work

V súčasnosti je viac známe poškodenie neurónov pri neurodegeneratívnych chorobách CNS ako poškodenie neuroglií, konkrétne makro či mikro. Témou bakalárskej práce by bolo vypracovanie prehľadu súčasného stavu poznania morfologických, histologických a imunohistochemických zmien v neuroglii v súvislosti s hlavnými skupinami neurodegeneratívnych chorôb (Alzheimerova demencia, vaskulárna demencia) u človeka, poprípade v experimentálnom modeli na zvierati.

Preliminary scope of work in English

In the present literatue concerning neurodegenerative disorders of the CNS there are more numerous data concerning neuronal lesions compared to neuroglial defects (both macro as well as micro). The topic of the bachelor thesis thus would be elaboration on present state of knowledge of morphological, histological and immunohistochemical changes in the neuroglia with accent to major groups of neurodegenerative disorders (Alzheimer disease, vascular dementia) in human as well as in experimental animal.