Studium vlastností biodegradovatelných nanočástic na bázi polyesterů
| Thesis title in Czech: | Studium vlastností biodegradovatelných nanočástic na bázi polyesterů |
|---|---|
| Thesis title in English: | A study of biodegradable polyesters based nanoparticles properties |
| Key words: | nanočástice, biodegradace, stabilita, PLGA |
| English key words: | nanoparticles, biodegradability, stability, PLGA |
| Academic year of topic announcement: | 2020/2021 |
| Thesis type: | rigorosum thesis |
| Thesis language: | čeština |
| Department: | Department of Pharmaceutical Technology (16-16210) |
| Supervisor: | PharmDr. Ondřej Holas, Ph.D. |
| Author: | hidden - assigned and confirmed by the Study Dept. |
| Date of registration: | 05.11.2020 |
| Date of assignment: | 05.11.2020 |
| Confirmed by Study dept. on: | 05.11.2020 |
| Date and time of defence: | 14.01.2021 00:00 |
| Date of electronic submission: | 06.01.2021 |
| Date of proceeded defence: | 14.01.2021 |
| Opponents: | doc. RNDr. Milan Dittrich, CSc. |
| Guidelines |
| Student se seznámí s odbornou literaturou a dostupnými laboratorními postupy. Následovat bude bude práce v laboratoři zahrnující přípravu a hodnocení farmaceutických formulací na bázi polymerních nosičů. |
| References |
| Tammam S.N., Azzazy H.M.E., Lamprecht, A. Biodegradable Particulate Carrier Formulation and Tuning for Targeted Drug Delivery. J. Biomed. Nanotechnol. 2015, 11, 555-577 Hans M.L., Lowman A.M. Biodegradable nanoparticles for drug delivery and targeting, Curr. Opp. Sol. St. Mat. Sci. 2002, 6, 319-327 Hickey J.W., Santos J.L., Williford J.M., Mao H.Q. Control of polymeric nanoparticle size to improve therapeutic delivery, J. Control Release, 2015, 10, 536-547 Rao J.P., Gelecker H.E. Polymer nanoparticles: Preparation techniques and size-control parameters, 2011, 36, 887-913 Bennet D., Kim S. 2014, Polymer nanoparticles for smart drug delivery, Application of Nanotechnology in Drug Delivery, PhD. Ali Demir Sezer (Ed.), InTech, DOI: 10.5772/58422 |
| Preliminary scope of work |
| Příprava nanočástic s enkpsulovanýcm léčivem Stabilitní testy Hodnocení enkapsulační efektivita Sepsání práce |
| Preliminary scope of work in English |
| Preparation of drug loaded nanoparticles Stability testing Encapsulation efficiency assessment Writing a thesis |