Thesis (Selection of subject)Thesis (Selection of subject)(version: 336)
Assignment details
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Fotodynamická inaktivace mikroorganismů (aza)ftalocyaninovými fotosensitizéry
Thesis title in Czech: Fotodynamická inaktivace mikroorganismů (aza)ftalocyaninovými fotosensitizéry
Thesis title in English: Photodynamic inactivation of microorganisms using (aza)phthalocyanine photosensitisers
Academic year of topic announcement: 2019/2020
Type of assignment: diploma thesis
Thesis language: čeština
Department: Department of Biochemical Sciences (16-16160)
Supervisor: RNDr. Miloslav Macháček, Ph.D.
Author: hidden - assigned by the advisor
Date of registration: 23.10.2019
Date of assignment: 17.12.2019
Date and time of defence: 01.06.2021 09:00
Date of electronic submission:14.05.2021
Date of proceeded defence: 01.06.2021
Reviewers: PharmDr. Jan Kollár, Ph.D.
 
 
 
Advisors: RNDr. Klára Konečná, Ph.D.
Guidelines
1. Seznámení se s odbornou literaturou a vypracování rešerše.
2. Nácvik potřebných metodik (základy práce v mikrobiologické laboratoři, kultivace suspenzních kultur a tvorba biofilmů)
3. Samostatná experimentální práce.
4. Zpracování a hodnocení dat.
5. Sepsání diplomové práce
References
Tim M. Strategies to optimize photosensitizers for photodynamic inactivation of bacteria. Journal of Photochemistry and Photobiology B: Biology 150 (2015) 2–10. doi: 10.1016/j.jphotobiol.2015.05.010
Cieplik F, Deng D, Crielaard W, Buchalla W, Hellwig E, Al-Ahmad A, Maisch T. Antimicrobial photodynamic therapy – what we know and what we don’t. Critical Reviews in Microbiology, 44:5, 571-589, DOI: 10.1080/1040841X.2018.1467876
Huang L, Dai R, Hamblin MR. Antimicrobial Photodynamic Inactivation and Photodynamic Therapy for Infections. Methods Mol Biol. 2010 ; 635: 155–173. doi:10.1007/978-1-60761-697-9_12
Nunes da Silva R, Cunha Â, Tomé AC. Phthalocyanine–sulfonamide conjugates: Synthesis and photodynamic inactivation of Gram-negative and Gram-positive bacteria. European Journal of Medicinal Chemistry. Volume 154, 25 June 2018, Pages 60-67. doi: 10.1016/j.ejmech.2018.05.009
Tong W, Xiong Y, Duan S, Ding X, Xu F-J. Phthalocyanine functionalized poly(glycidyl methacrylate) nano-assemblies for photodynamic inactivation of bacteria. Biomater. Sci., 2019, 7, 1905-1918. doi: 10.1039/C8BM01483C
Grüner MC, Niemann S, Faust A, Strassert CA. Axially Decorated SiIV-phthalocyanines Bearing Mannose- or Ammonium-conjugated Siloxanes: Comparative Bacterial Labeling and Photodynamic Inactivation. Photochemistry and Photobiology, 2018, 94: 890–899. doi: 10.1111/php.12881
 
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