Reporter gene studies for nanoparticle mediated DNA and siRNA delivery.
| Thesis title in Czech: | Transfekce DNA a siRNA pomocí nanočástic: studium pomocí gene reporter assay. |
|---|---|
| Thesis title in English: | Reporter gene studies for nanoparticle mediated DNA and siRNA delivery. |
| Key words: | transfekce, plasmidvá DNA, siRNA, nanočástice |
| English key words: | transfection, plasmid DNA, siRNA, nanoparticles |
| Academic year of topic announcement: | 2017/2018 |
| Type of assignment: | rigorosum thesis |
| Thesis language: | angličtina |
| Department: | Department of Biochemical Sciences (16-16160) |
| Supervisor: | PharmDr. Anna Jirkovská, Ph.D. |
| Author: | hidden - assigned and confirmed by the Study Dept. |
| Date of registration: | 07.06.2018 |
| Date of assignment: | 07.06.2018 |
| Confirmed by Study dept. on: | 07.06.2018 |
| Date and time of defence: | 27.06.2018 00:00 |
| Date of electronic submission: | 07.06.2018 |
| Date of proceeded defence: | 27.06.2018 |
| Reviewers: | doc. RNDr. Jakub Hofman, Ph.D. |
| Guidelines |
| Zvládnutí aseptických technik pro práci s buněčnými liniemi. Samostatné vyhodnocení dat včetně grafického a statistického zpracování. Vypracování rešerše literatury vztahující se k tématu, diskuse výsledků práce. |
| References |
| Jin L., et al. Current progress in gene delivery technology based on chemical methods and nano-carriers. Theranostics, 2014, 4(3):240-255. Scholz C., Wagner E. Therapeutic plasmid DNA versus siRNA delivery: Common and different tasks for synthetic carriers. Journal of controlled release, 2012, 161: 554-565. Kesharwani P. et al. A review of nanocarriers for the delivery of small interfering RNA. Biomaterials, 2012, 33: 7138-7150. |