Vliv endokrinních disruptorů na expresi a aktivitu cytochromů P450 2B v modelovém organismu potkana
| Thesis title in Czech: | Vliv endokrinních disruptorů na expresi a aktivitu cytochromů P450 2B v modelovém organismu potkana |
|---|---|
| Thesis title in English: | The effects of endocrine disruptors on the expression and the activity of cytochromes P450 2B in laboratory rat as a model organism |
| Key words: | endokrinní disruptory, benzo[a]pyren, ethinylestradiol, estradiol, cytochrom P450 2B, exprese, aktivita, indukce |
| English key words: | endocrine disruptors, benzo[a]pyrene, ethinylestradiol, estradiol, cytochrome P450 2B, expression, activity, induction |
| Academic year of topic announcement: | 2017/2018 |
| Thesis type: | Bachelor's thesis |
| Thesis language: | čeština |
| Department: | Department of Biochemistry (31-250) |
| Supervisor: | RNDr. Helena Dračínská, Ph.D. |
| Author: | hidden - assigned by the advisor |
| Date of registration: | 13.11.2017 |
| Date of assignment: | 16.11.2017 |
| Date of electronic submission: | 25.05.2018 |
| Date of proceeded defence: | 12.06.2018 |
| Opponents: | RNDr. Kateřina Levová, Ph.D. |
| Preliminary scope of work |
| Studium vlivu endokrinních disruptorů na genovou a proteinovou expresi a aktivitu cytochromů P450 podrodiny 2B v modelovém organismu potkana. Metody: kvantitativní PCR, Westernblot s následnou imunodetekcí, měření enzymové aktivity |