Molekulárna stavba konštitutívneho heterochromatínu

• Thesis title in thesis language (Slovak): Molekulárna stavba konštitutívneho heterochromatínu
• Thesis title in Czech: Molekulární stavba konstitutivního heterochromatinu
• Thesis title in English: Molecular composition of constitutive heterochromatin
• Key words: centromera, DNA, histon, HP1, konstitutivní heterochromatin, metylace, modifikace, protein, RNA, specifický, telomera
• English key words: centromere, DNA, histone, HP1, constitutive heterochromatin, methylation, modification, protein, RNA, specific, telomere
• Academic year of topic announcement: 2015/2016
• Thesis type: Bachelor's thesis
• Thesis language: slovenština
• Department: Department of Genetics and Microbiology (31-140)
• Supervisor: doc. RNDr. Jiří Král, CSc.
• Author: hidden - assigned by the advisor
• Date of registration: 20.10.2015
• Date of assignment: 20.10.2015
• Date of electronic submission: 09.05.2016
• Date of proceeded defence: 06.06.2016
• Opponents: doc. RNDr. Dana Holá, Ph.D.

Preliminary scope of work

Práce bude zaměřena na specifické molekulární znaky konstitutivního heterochromatinu, tedy na úroveň DNA, proteinů a RNA, jakož i na to, jakým způsobem tyto modifikace podmiňují stavbu a funkci tohoto typu chromatinu.

Preliminary scope of work in English

This study will be focused on specific molecular features of constitutive heterochromatin (level of DNA, RNA, proteins). I will be shown how these modifications influence structure and function of this type of chromatin.