Prokaryotic proteins of antioxidant defense in Trichomonas vaginalis hydrogenosomes

• Thesis title in Czech: Prokaryotické proteíny antioxidačnej obrany v hydrogenozómoch Trichomonas vaginalis
• Thesis title in English: Prokaryotic proteins of antioxidant defense in Trichomonas vaginalis hydrogenosomes
• Key words: Trichomonas, hydrogenosom, flavodiiron protein, FeS flavoprotein, glycin dekarboxyláza
• English key words: Trichomonas, hydrogenosome, flavodiiron protein, FeS flavoprotein, glycine cleavage system
• Academic year of topic announcement: 2006/2007
• Thesis type: dissertation
• Thesis language: angličtina
• Department: Department of Parasitology (31-161)
• Supervisor: doc. RNDr. Ivan Hrdý, Ph.D.
• Author: hidden - assigned by the advisor
• Date of registration: 09.03.2010
• Date of assignment: 09.03.2010
• Date and time of defence: 28.04.2016 13:00
• Date of electronic submission: 10.03.2016
• Date of proceeded defence: 28.04.2016
• Opponents: doc. RNDr. Anton Horváth, CSc.
• Advisors: prof. RNDr. Jan Tachezy, Ph.D.

Preliminary scope of work

Cílem je charakterizovat proteiny prokaryotického typu identifikované během anotace genomu parazita Trichomonas vaginalis. Předpokládáme, že proteiny se účastní dosud neznámých redoxních pochodů v hydrogenosomech trichomonády, pravděpodobně při obraně organely proti oxidativnímu stresu.

Preliminary scope of work in English

The aim is to characterize bacterial-type proteins identified during the annotation of Trichomonas vaginalis genome. We assume that the proteins participate in so far unknown redox processes in trichomonad hydrogenosomes, likely in antioxidant defense of the organelle.