Preparation and evaluation of targeted drug nanoformulation
| Thesis title in Czech: | Příprava a hodnocení nanoformulací pro cílenou distribuci léčiv |
|---|---|
| Thesis title in English: | Preparation and evaluation of targeted drug nanoformulation |
| Key words: | Cílené formulace, nanočátice, pasivní targeting, aktivní targeting |
| English key words: | Targeted Drug Delivery, Nanoparticles, Passive Targeting, Active Targeting |
| Academic year of topic announcement: | 2024/2025 |
| Thesis type: | rigorosum thesis |
| Thesis language: | angličtina |
| Department: | Department of Pharmaceutical Technology (16-16210) |
| Supervisor: | prof. PharmDr. Petr Pávek, Ph.D. |
| Author: | hidden - assigned and confirmed by the Study Dept. |
| Date of registration: | 01.10.2018 |
| Date of assignment: | 01.10.2018 |
| Confirmed by Study dept. on: | 02.07.2025 |
| Date and time of defence: | 30.06.2025 00:00 |
| Date of electronic submission: | 12.12.2024 |
| Date of proceeded defence: | 30.06.2025 |
| Opponents: | doc. PharmDr. Andrej Kováčik, Ph.D. |
| doc. RNDr. Aleš Panáček, Ph.D. | |
| Advisors: | PharmDr. Ondřej Holas, Ph.D. |
| Guidelines |
| 1. literární rešerše
2. experimentální práce 3. publikace a prezentace výsledků 4. obhajoba |
| References |
| Tammam S.N., Azzazy H.M.E., Lamprecht, A. Biodegradable Particulate Carrier Formulation and Tuning for Targeted Drug Delivery. J. Biomed. Nanotechnol. 2015, 11, 555-577
Hans M.L., Lowman A.M. Biodegradable nanoparticles for drug delivery and targeting, Curr. Opp. Sol. St. Mat. Sci. 2002, 6, 319-327 Hickey J.W., Santos J.L., Williford J.M., Mao H.Q. Control of polymeric nanoparticle size to improve therapeutic delivery, J. Control Release, 2015, 10, 536-547 Rao J.P., Gelecker H.E. Polymer nanoparticles: Preparation techniques and size-control parameters, 2011, 36, 887-913 Bennet D., Kim S. 2014, Polymer nanoparticles for smart drug delivery, Application of Nanotechnology in Drug Delivery, PhD. Ali Demir Sezer (Ed.), InTech, DOI: 10.5772/58422 |
| Preliminary scope of work |
| 1. příprava formulací
2. biologické hodnocení formulací 3. hodnocení výsledků 4. optimalizace parametrů formulací 5. Prazentace výsledků |
| Preliminary scope of work in English |
| 1. Preparation of formulations
2. Biological assessment 3. Results evaluation 4. Parameter optimization 5. Presentation of results |