Vliv infekce motolicí Trichobilharzia szidati na průběh schistosomózy v myším modelu
| Thesis title in Czech: | Vliv infekce motolicí Trichobilharzia szidati na průběh schistosomózy v myším modelu |
|---|---|
| Thesis title in English: | The effect of Trichobilharzia szidati infection on the course of schistosomosis in a mouse model |
| Academic year of topic announcement: | 2024/2025 |
| Thesis type: | diploma thesis |
| Thesis language: | čeština |
| Department: | Department of Parasitology (31-161) |
| Supervisor: | RNDr. Tomáš Macháček, Ph.D. |
| Author: | hidden - assigned and confirmed by the Study Dept. |
| Date of registration: | 01.10.2024 |
| Date of assignment: | 03.10.2024 |
| Confirmed by Study dept. on: | 22.12.2024 |
| Guidelines |
| MB160P33 Biologie helmintů MB160P75E Parasite Immunology MB160C70 Praktická analýza a vizualizace laboratorních dat MB151P80 Cytometrie |
| References |
| Christensen, N. Ø., Nansen, P., Fagbemi, B. O., & Monrad, J. (1987). Heterologous antagonistic and synergistic interactions between helminths and between helminths and protozoans in concurrent experimental infection of mammalian hosts. Parasitology Research, 73(5), 387-410. Kouřilová, P., & Kolářová, L. (2002). Variations in immunofluorescent antibody response against Trichobilharzia and Schistosoma antigens in compatible and incompatible hosts. Parasitology Research, 88(6), 513–521. Pedersen, E. M., Christensen, N. Ø., & Frandsen, F. (1982). Reduction in the severity of hepatosplenic schistosomiasis mansoni in mice by previous exposure to cercariae of the bird schistosome Trichobilharzia szidati. Journal of Helminthology, 56(01), 1-3. |
| Preliminary scope of work |
| Studium potenciálního protektivního vlivu infekce trichobilharziemi na průběh myší schistosomózy. Infekce myší motolicí Trichobilharzia szizdati a následně v odstupu Schistosoma mansoni. Analýza patologie a hostitelské imunitní odpovědi. Hlavní použité metody: parazitologická pitva, histologie, průtoková cytometrie, ELISA. |