Mechanistické simulace dynamických laterálních efektů v primární zrakové kůře kočky

• Thesis title in Czech: Mechanistické simulace dynamických laterálních efektů v primární zrakové kůře kočky
• Thesis title in English: Mechanistic simulations of dynamic lateral effects in the cat primary visual cortex
• Academic year of topic announcement: 2023/2024
• Thesis type: dissertation
• Thesis language: čeština
• Department: Department of Software and Computer Science Education (32-KSVI)
• Supervisor: Mgr. Ján Antolík, Ph.D.
• Author: hidden - assigned and confirmed by the Study Dept.
• Date of registration: 20.03.2024
• Date of assignment: 20.03.2024
• Confirmed by Study dept. on: 21.03.2024

Guidelines

The goal of this project is to understand how lateral interactions in cortical visual neural networks (primarily V1) shape the dynamic recurrent activity both during spontaneous, visually evoked and externally evoked (primarily optogenetically evoked condition. This project will involve:
(a) developing the necessary improvements of existing detailed large scale model of primary visual cortex [1] to model the three target conditions
(b) developing the various visual or external stimulation protocols to reproduce experimental design in reference in-vivo studies
(c) develop analysis to assess the emergence of the target phenomena in the V1 model and formulate predictions

References

[1] Antolík, J, Monier, C., Davison, A., Frégnac Y.; A comprehensive data-driven model of cat primary visual cortex. bioRxiv, 416156
[2] Antolík, J., & Davison, A. P. (2013). Integrated workflows for spiking neuronal network simulations. Frontiers in Neuroinformatics, 7(December), 1–15. https://doi.org/10.3389/fninf.2013.00034
[3] Antolik, J., Sabatier, Q., Galle, C., & Frégnac Y. (2019). Cortical visual prosthesis : a detailed large-scale simulation study.[4] Dayan & Abbott (2005) Theoretical Neuroscience: Computational and Mathematical Modeling of Neural Systems