Cyclodextrin-drug conjugates - synthesis and study of their properties

• Thesis title in Czech: Konjugáty cyklodextrin-léčivo - syntéza a studium jejich vlastností
• Thesis title in English: Cyclodextrin-drug conjugates - synthesis and study of their properties
• Key words: cyklodextrin; léčivo; konjugát; properties
• English key words: cyclodextrin; drug; conjugate; properties
• Academic year of topic announcement: 2022/2023
• Thesis type: diploma thesis
• Thesis language: angličtina
• Department: Department of Organic Chemistry (31-270)
• Supervisor: doc. RNDr. Jindřich Jindřich, CSc.
• Author: hidden - assigned and confirmed by the Study Dept.
• Date of registration: 18.01.2023
• Date of assignment: 18.01.2023
• Confirmed by Study dept. on: 01.02.2023

Preliminary scope of work

Náplní práce bude syntéza konjugátů alfa- a beta-cycklodextrinu s fluorouracilem za využití různých kovalentních spojek. a studium jejich chemické stability a self-inkluze.

Preliminary scope of work in English

The content of the thesis will be the synthesis of alpha- and beta-cyclodextrin conjugates with fluorouracil using various covalent linkers and the study of their chemical stability and self-inclusion.