The influence of micronized poloxamer on the flow and compaction of a model tableting mixture

• Thesis title in Czech: Vliv mikronizovaného poloxameru na sypnost a lisovatelnost modelové tabletoviny
• Thesis title in English: The influence of micronized poloxamer on the flow and compaction of a model tableting mixture
• Key words: sypnost, pomocné látky, lubrikanty, lisovatelnost, tablety
• English key words: flowability, excipients, lubricants, compressibility, tablets
• Academic year of topic announcement: 2021/2022
• Thesis type: diploma thesis
• Thesis language: angličtina
• Department: Department of Pharmaceutical Technology (16-16210)
• Supervisor: doc. PharmDr. Zdeňka Šklubalová, Ph.D.
• Author: hidden - assigned by the advisor
• Date of registration: 16.09.2021
• Date of assignment: 17.02.2023
• Date and time of defence: 01.06.2023 12:15
• Date of electronic submission: 09.05.2023
• Date of proceeded defence: 01.06.2023
• Opponents: PharmDr. Petra Svačinová, Ph.D.
• Advisors: Sebastien Edward Francis Bailey

Guidelines

1. Introduction, literature review
2. Experimental work
3. Evaluation of results
4. Manuscript processing

References

Ph.Eur. 11.0 + suppl, USP
Gad, S.C.: Pharmaceutical manufacturing handbook. Production and processes. Wiley-Interscience, Hoboken, New Jersey, 2003, 1370 S
Box, G.E.P., Hunter, J. S., Hunter, W.G.: Statistics for experimenters. 2nd. Ed., Wiley - Interscience, Hoboken, New Jersey, 2005, 639 S
Actual articles : Part. Sci. Technol., Powder Technol. Int.J.Pharm., Drug Dev.Ind.Pharm, Powder Technol., Granular matter, Eur. J. Pharm. Sci.

Preliminary scope of work in English

Formulation study using excipients, characterisation of flowability, consolidation, preparation of powder mixtures, compression of tablets, evaluation of tablets