Studium vlivu povrchově aktivních látek na parametry polymerních nanočástic
| Thesis title in Czech: | Studium vlivu povrchově aktivních látek na parametry polymerních nanočástic |
|---|---|
| Thesis title in English: | Study of the surfactants effect on polymer nanoparticle parameters |
| Key words: | nanočástice, nanoprecipitace, polyestery, in vitro, povrchově aktivní látky |
| English key words: | nanoparticles, nanoprecipitation, polyesters, in vitro, surfactants |
| Academic year of topic announcement: | 2020/2021 |
| Thesis type: | rigorosum thesis |
| Thesis language: | čeština |
| Department: | Department of Pharmaceutical Technology (16-16210) |
| Supervisor: | PharmDr. Ondřej Holas, Ph.D. |
| Author: | hidden - assigned and confirmed by the Study Dept. |
| Date of registration: | 23.07.2021 |
| Date of assignment: | 23.07.2021 |
| Confirmed by Study dept. on: | 23.07.2021 |
| Date and time of defence: | 30.09.2021 00:00 |
| Date of electronic submission: | 20.09.2021 |
| Date of proceeded defence: | 30.09.2021 |
| Opponents: | PharmDr. Eva Šnejdrová, Ph.D. |
| Guidelines |
| Student se seznámí s odbornou literaturou a dostupnými laboratorními postupy. Následovat bude bude práce v laboratoři zahrnující přípravu farmaceutických formulací na bázi polymerních nosičů. |
| References |
| Tammam S.N., Azzazy H.M.E., Lamprecht, A. Biodegradable Particulate Carrier Formulation and Tuning for Targeted Drug Delivery. J. Biomed. Nanotechnol. 2015, 11, 555-577 Hans M.L., Lowman A.M. Biodegradable nanoparticles for drug delivery and targeting, Curr. Opp. Sol. St. Mat. Sci. 2002, 6, 319-327 Hickey J.W., Santos J.L., Williford J.M., Mao H.Q. Control of polymeric nanoparticle size to improve therapeutic delivery, J. Control Release, 2015, 10, 536-547 Bennet D., Kim S. 2014, Polymer nanoparticles for smart drug delivery, Application of Nanotechnology in Drug Delivery, PhD. Ali Demir Sezer (Ed.), InTech, DOI: 10.5772/5842 Gaunachaud F., Katz J.L. Nanoparticles and Nanocapsules Created Using the Ouzo Effect: Spontaneous Emulsification as an Alternative to Ultrasonic and High-Shear Devices, Chem. Phys. Chem 2005, 6, 209 – 216 |
| Preliminary scope of work |
| Optimalizace přípravy nanočástic Studium vlivu pomocných látek na tvorbu a separaci nanočástic Hodnocení parametrů připravených částic |
| Preliminary scope of work in English |
| Optimization of nanoparticle preparation Study of the excipients influence on the formation and separation of nanoparticles Evaluation of parameters of prepared particles |