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Vliv pH a dalších faktorů na metabolické přeměny tyrosinkinasových inhibitorů.
Thesis title in Czech: | Vliv pH a dalších faktorů na metabolické přeměny tyrosinkinasových inhibitorů. |
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Thesis title in English: | Effect of pH and other factors on the metabolic conversion of tyrosine kinase inhibitors. |
Key words: | vandetanib, sunitinib, cytochromy P450, flavinmonooxygenasy |
English key words: | vandetanib, sunitinib, cytochrome P450, flavin-containing monooxygenases |
Academic year of topic announcement: | 2020/2021 |
Thesis type: | diploma thesis |
Thesis language: | čeština |
Department: | Department of Biochemistry (31-250) |
Supervisor: | Mgr. Radek Indra, Ph.D. |
Author: | hidden![]() |
Date of registration: | 14.11.2020 |
Date of assignment: | 27.11.2020 |
Confirmed by Study dept. on: | 27.11.2020 |
Date of electronic submission: | 13.05.2023 |
Date of proceeded defence: | 30.05.2023 |
Opponents: | RNDr. Michaela Čermáková, Ph.D. |
Preliminary scope of work |
Studium vlivu pH a teploty na metabolismus tyrosinkinasových inhibitorů cytochromy P450, flavinmonooxygenasamy a dalšími biotransformačními enzymy. |