Vliv NADPH:cytochrom P450 reduktasy a cytochromu b5 na metabolismus vandetanibu cytochromem P450 3A5
| Thesis title in Czech: |
Vliv NADPH:cytochrom P450 reduktasy a cytochromu b5 na metabolismus vandetanibu cytochromem P450 3A5 |
| Thesis title in English: |
The effect of NADPH:cytochrome P450 reductase and cytochrome b5 on metabolism of vandetanib by cytochrome P450 3A5 |
| Key words: |
rakovina, vandetanib, cytochrom P450, tyrosinkinasové inhibitory |
| English key words: |
cancer; vandetanib; cytochromes P450; tyrosine kinase inhibitors |
| Academic year of topic announcement: |
2019/2020 |
| Thesis type: |
Bachelor's thesis |
| Thesis language: |
čeština |
| Department: |
Department of Biochemistry (31-250) |
| Supervisor: |
Mgr. Radek Indra, Ph.D. |
| Author: |
hidden - assigned by the advisor, waiting for guarantor's approval |
| Date of registration: |
23.10.2019 |
| Date of assignment: |
23.10.2019 |
| Date of electronic submission: | 10.06.2020 |
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| Date of proceeded defence: |
29.07.2020 |
| Opponents: |
RNDr. Iveta Mrízová, Ph.D. |
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| Preliminary scope of work |
| Vliv cytochromů P450 exprimovaných v systému E. coli na oxidaci vandetanibu a porovnání tohoto expresního systému s eukaryotním expresním systémem. |
