The role of energy metabolism in cardioprotection induced by the adaptation to chronic hypoxia

• Thesis title in Czech: Úloha energetického metabolismu v kardioprotekci indukované adaptací na chronickou hypoxii
• Thesis title in English: The role of energy metabolism in cardioprotection induced by the adaptation to chronic hypoxia
• Key words: srdce, energetický metabolismus, mitochondrie, peroxisom, glykolýza, beta-oxidace, chronická hypoxie
• English key words: heart, energy metabolism, mitochondria, peroxisome, glycolysis, beta-oxidation, chronic hypoxia
• Academic year of topic announcement: 2013/2014
• Thesis type: dissertation
• Thesis language: angličtina
• Department: Department of Physiology (31-152)
• Supervisor: doc. RNDr. Jitka Žurmanová, Ph.D.
• Author: hidden - assigned by the advisor
• Date of registration: 04.12.2013
• Date of assignment: 04.12.2013
• Date and time of defence: 21.09.2018 11:00
• Date of electronic submission: 22.06.2018
• Date of proceeded defence: 21.09.2018
• Opponents: prof. MUDr. Michaela Adamcová, Ph.D.

Preliminary scope of work

Cílem práce je prozkoumat energetický metaboslismus srdce potkana adaptovaného na hypoxii a pokusit se odhalit významné změny, které přispívají ke kardioprotektivnímu fenotypu.

Preliminary scope of work in English

The major aim of the thesis is to determine the alterations of energy metabolism of the rat heart adpated to chronic hypoxia and to evaluate these chanages which contribute to the cardioprotective phenotype.