Thesis (Selection of subject)Thesis (Selection of subject)(version: 390)
Thesis details
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Diabetes mellitus 2. typu a Alzheimerova demence: studium společných patogenetických faktorů
Thesis title in Czech: Diabetes mellitus 2. typu a Alzheimerova demence: studium společných patogenetických faktorů
Thesis title in English: Study of Common Pathogenetic Factors of Alzheimer Disease and Type 2 Diabetes Mellitus
Key words: Alzheimerova demence, diabetes mellitus 2. typu, inzulínová rezistence, visfatin, riziková alela ε4, polymorfismus genu BIN1
English key words: Alzheimer's disease, type 2 diabetes mellitus, insulin resistance, visfatin, risk ε4 allele, a polymorphism of the gene BIN1
Academic year of topic announcement: 2012/2013
Thesis type: diploma thesis
Thesis language: čeština
Department: Department of Anthropology and Human Genetics (31-110)
Supervisor: RNDr. Markéta Vaňková, Ph.D.
Author: hidden - assigned by the advisor, waiting for guarantor's approval
Date of registration: 31.10.2012
Date of assignment: 21.11.2012
Date of electronic submission:11.08.2014
Date of proceeded defence: 09.09.2014
Opponents: RNDr. Mgr. Petra Lukášová, Ph.D.
 
 
 
Preliminary scope of work
Diplomant/ka by se podílel/a na sběru fenotypických dat (podrobné antropometrické vyšetření, dotazníková data, biochemie) a na genetických analýzách vybraných kandidátních genů pro diabetes 2. typu a Alzheimerovy demence. Soubory budou zahrnovat pacienty s diabetem, AD a kontrolní jedince. Na Endokrinologickém ústavu v Praze právě probíhá výzkumný projekt na toto téma, diplomová práce by byla součástí této studie.
Preliminary scope of work in English
Student should be involved in the collection of phenotypic data (detailed anthropometric examination, questionnaire data, biochemistry) and the genetic analysis of selected candidate genes for type 2 diabetes and Alzheimer's disease. The files will include patients with diabetes, AD and control subjects. The Institute of Endocrinology in Prague is ongoing research project on this topic, thesis would be part of the study.
 
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