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Protein profiling, metabolic enzymes and transmembrane signaling in the heart of spontaneously hypertensive SHR-Tg19 rat
Thesis title in Czech:
Proteinový profil, metabolické enzymy a transmembránová signalizace v myokardu spontánně hypertenzního potkana kmene SHR-Tg19
Thesis title in English:
Protein profiling, metabolic enzymes and transmembrane signaling in the heart of spontaneously hypertensive SHR-Tg19 rat
Key words:
SHR, Cd36, Srdce, Levá a pravá komory, proteomika, mitochondrie
English key words:
SHR, Cd36, Heart, Left and right ventricles, proteomics, mitochondria
Academic year of topic announcement:
2012/2013
Thesis type:
dissertation
Thesis language:
angličtina
Department:
Department of Physiology (31-152)
Supervisor:
doc. RNDr. Jiří Novotný, DSc.
Author:
hidden - assigned by the advisor
Date of registration:
08.10.2012
Date of assignment:
08.10.2012
Date and time of defence:
14.12.2018 13:00
Date of electronic submission: 11.10.2018
Date of proceeded defence:
14.12.2018
Opponents:
prof. MUDr. Jitka Kuncová, Ph.D.
doc. RNDr. Martin Kalous, CSc.
Preliminary scope of work
Cílem práce je zkoumat vliv trangenní exprese Cd36 v potkanech SHR na proteom srdce, na funkci vybraných metabolických enzymů a na expresi a distribuci vybraných komponent adrenergní transmembránové signalizce.