Súčasné trendy v terapii dyslipidémií
Název práce v jazyce práce (slovenština): | Súčasné trendy v terapii dyslipidémií |
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Název práce v češtině: | Současné trendy v terapií dyslipidémií |
Název v anglickém jazyce: | Current trends in dyslipidemia therapy |
Akademický rok vypsání: | 2020/2021 |
Typ práce: | diplomová práce |
Jazyk práce: | slovenština |
Ústav: | Katedra biologických a lékařských věd (16-16150) |
Vedoucí / školitel: | prof. PharmDr. Petr Nachtigal, Ph.D. |
Řešitel: | skrytý![]() |
Datum přihlášení: | 29.09.2021 |
Datum zadání: | 23.02.2023 |
Datum a čas obhajoby: | 30.05.2023 08:00 |
Datum odevzdání elektronické podoby: | 05.05.2023 |
Datum proběhlé obhajoby: | 30.05.2023 |
Oponenti: | PharmDr. Katarína Tripská, Ph.D. |
Zásady pro vypracování |
Literární rešerše Praktická experimentální část Sepsání diplomové práce Obhajoba diplomové práce |
Seznam odborné literatury |
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Stroke 40, 439-447 5. St-Jacques, S., Forte, M., Lye, S. J., and Letarte, M. (1994) Localization of endoglin, a transforming growth factor-beta binding protein, and of CD44 and integrins in placenta during the first trimester of pregnancy. Biol Reprod 51, 405-413 6. Meurer, S., Wimmer, A. E., van de Leur, E., and Weiskirchen, R. (2019) Endoglin Trafficking/Exosomal Targeting in Liver Cells Depends on N-Glycosylation. Cells 8, 997 7. Lastres, P., Bellon, T., Cabanas, C., Sanchez-Madrid, F., Acevedo, A., Gougos, A., Letarte, M., and Bernabeu, C. (1992) Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen. Eur J Immunol 22, 393-397 8. Aristorena, M., Gallardo-Vara, E., Vicen, M., de Las Casas-Engel, M., Ojeda-Fernandez, L., Nieto, C., Blanco, F. J., Valbuena-Diez, A. C., Botella, L. M., Nachtigal, P., Corbi, A. L., Colmenares, M., and Bernabeu, C. 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(2005) Intermittent high glucose enhances ICAM-1, VCAM-1 and E-selectin expression in human umbilical vein endothelial cells in culture: the distinct role of protein kinase C and mitochondrial superoxide production. Atherosclerosis 183, 259-267 27. Hemling, P., Zibrova, D., Strutz, J., Sohrabi, Y., Desoye, G., Schulten, H., Findeisen, H., Heller, R., Godfrey, R., and Waltenberger, J. (2020) Hyperglycemia-induced endothelial dysfunction is alleviated by thioredoxin mimetic peptides through the restoration of VEGFR-2-induced responses and improved cell survival. Int J Cardiol 308, 73-81 28. Lv, Z. H., Phuong, T. A., Jin, S. J., Li, X. X., and Xu, M. (2017) Protection by simvastatin on hyperglycemia-induced endothelial dysfunction through inhibiting NLRP3 inflammasomes. Oncotarget 8, 91291-91305 29. La Sala, L., Pujadas, G., De Nigris, V., Canivell, S., Novials, A., Genovese, S., and Ceriello, A. (2015) Oscillating glucose and constant high glucose induce endoglin expression in endothelial cells: the role of oxidative stress. Acta Diabetol 52, 505-512 30. Sanchez-Elsner, T., Botella, L. M., Velasco, B., Langa, C., and Bernabeu, C. (2002) Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways. J Biol Chem 277, 43799-43808 31. van Uden, P., Kenneth, N. S., and Rocha, S. (2008) Regulation of hypoxia-inducible factor-1alpha by NF-kappaB. Biochem J 412, 477-484 32. Kumar, S., Pan, C. C., Bloodworth, J. C., Nixon, A. B., Theuer, C., Hoyt, D. G., and Lee, N. Y. (2014) Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling. Oncogene 33, 3970-3979 33. Blankenberg, S., Barbaux, S., and Tiret, L. (2003) Adhesion molecules and atherosclerosis. Atherosclerosis 170, 191-203 34. Liu, Y., Starr, M. D., Brady, J. C., Dellinger, A., Pang, H., Adams, B., Theuer, C. P., Lee, N. Y., Hurwitz, H. I., and Nixon, A. B. (2014) Modulation of circulating protein biomarkers following TRC105 (anti-endoglin antibody) treatment in patients with advanced cancer. Cancer Med 3, 580-591 |