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The analysis of pharmacotherapy by patients suffering with DM in Greece I
Název práce v češtině:
Název v anglickém jazyce: The analysis of pharmacotherapy by patients suffering with DM in Greece I
Klíčová slova anglicky: diabetes mellitus; cross sectional study; pharmacotherapy; real live; metformin, glitazons, glinids, incretin mimetics, insulins, sulfonylaryl urea; drug related problems
Akademický rok vypsání: 2012/2013
Typ práce: diplomová práce
Jazyk práce: angličtina
Ústav: Katedra sociální a klinické farmacie (16-16220)
Vedoucí / školitel: prof. RNDr. Jiří Vlček, CSc.
Řešitel: skrytý - zadáno vedoucím/školitelem
Datum přihlášení: 21.01.2013
Datum zadání: 21.01.2013
Datum a čas obhajoby: 10.02.2015 00:00
Datum odevzdání elektronické podoby:26.01.2015
Datum proběhlé obhajoby: 10.02.2015
Oponenti: PharmDr. Martin Doseděl, Ph.D.
Zásady pro vypracování
Aim: To analyze to strategy of treatment of DM and potential DRP
Introduction with aim
Theoretical part (literature from 2010) (bibliographic address): about 1/ DM; 2/ Strategy of treatment; 3/ Particular group of drugs; 4/ rate od use different drugs and combination; 5/ analysis of drug compliance (adherence), food compliance
Experimental part: 1/ Methods; 1.1/ Source of data; 1.2 How to collect them; 1.3/ Evaluation ( frequency analysis)
Seznam odborné literatury
Medline, PubMed search from 2002 - 2013
Clinical pharmacy and Therapeutics, edd. R. Walker & E. Clive, Elsevie science Limmited 2003; ISBN 0443 071373
Guidelines (Greek one (or international society for treatment of DM) e.g. Clinical Guidelines for Type 2 Diabetes Mellitus; European Diabetes Working Party for Older People 2001-2004
Předběžná náplň práce v anglickém jazyce
1/ literature search
2/ decision about methodology bruch a/ or b/ according avaibility of data in famuily pharmacy
Brunch a/ translate questionaire and let do pilot study about 10 patients
visitors coming into the pharmacy (prospective);
Inform consent that that they agree with this research
Questionnaire:Q0/ age, gender; Q1/ Duration of DM; Q2/ Type of DM :I know/I don´t know 3/ Do you know your: 3.1.Fasting glycaemia yes/no - if yes it is OK it high/low, in range; 3.2 Glycosylated hemoglobin let see 3.1/; 3.3/ Blood pressure /when did you measure it last time?;3.5/ Lipids; Q4:Did you not tolerate any antidiabetics in history……….Q5/ Do you suffer with adverse drug reaction? dug and what...; Q6 Do you use your drug according advice of physician: Yes, no; I forget sometimes at etc; Q7/ Do you think that composition of food take play a role in treatment your DM yes /no/ I don´t know; Q8 do use soame OTC drugs
Q9 do you suffer with another disesease
collect medicines + dosing scheme
questionnaire about diet from Hendrychova
Brunch b/ let do 10 patients Rp 1 -2year from patients asking for antidiabetic agents
From Rp (retrospective) All prescriptions with Dg DM; putze the data in Evaluated databases: 1/Antiabetic agents used 2/ Name patient or some ID; 3/ Age;4/ Gender; 5/ Day of dispensation; 6/ Name medicine, size, strength; 7/Way of administration o, sc, i.v.; 8/ Dosage scheme; cost

from brunch a/ or b/ analyze DRP: 1/ Missing of metformin, 2/ Rate of antidiabetics use; 3/ Duration of therapy and if time fit with dispensation; 4/ if you find the link how to identify another Rp from this particular patient:Drug/drug interactions and KI of drug in DM patient;
3step: to use methodology and collect data from 50 patients
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