velikost textu
Výsledky projektu Jak snižují regulační T buňky riziko vzniku autoimunity způsobené CD8+ T buňkami?
Výsledky
  Typ výsledku
Autor celku
Název celku(Celkem 5 zázn.)
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| Niederlova V, Tsyklauri O, Chadimova T, Stepanek O.. CD8+ Tregs revisited: A heterogeneous population with different phenotypes and properties.. European Journal of Immunology, 2021, sv. 51 (3), s. 512–530. ISSN 0014-2980. IF 5.532. [Článek v časopise] |
| Tsyklauri O, Niederlova V, Forsythe E, Prasai A, Drobek A, Kasparek P, Sparks K, Trachtulec Z, Prochazka J, Sedlacek R, Beales P, Huranova M, Stepanek O.. Bardet-Biedl Syndrome ciliopathy is linked to altered hematopoiesis and dysregulated self-tolerance.. EMBO Reports, 2021, sv. 22 (2), s. 1–18. ISSN 1469-221X. IF 8.807. [Článek v časopise] |
| Tsyklauri O, Chadimova T, Niederlova V, Kovarova J, Michalik J, Malatova I, Janusova S, Rossez H, Drobek A, Vecerova H, Galati V, Kovar M, Stepanek O., Preprint posted on bioRxiv: Tsyklauri O, Chadimova T, Niederlova V, Kovarova J, Michalik J, Malatova I, Janusova S, Rossez H, Drobek A, Vecerova H, Galati V, Kovar M, Stepanek O. Regulatory T cells suppress the formation of super-effector CD8 T cells by limiting IL-2. bioRxiv 2021.11.10.467495. [Jiný výsledek] |
| Tsyklauri Oksana, Figure 1. Preliminary results of GA UK project How Do Regulatory T Cells Reduce the Risk of Autoimmunity Mediated by CD8+ T Cells (A) Recombinant IL-2 interferes with Treg-mediated suppression of CD8+ T cell proliferation. (B-D) Tregs are unable to suppress autoimmunity in mice in the presence of IL-2 immunocomplexes (S4B6). (E-F) pSTAT5 and CD25 expression is upregulated in Treg-depleted mice. (G-H) Treg-depleted mice immunized with OVA, R4Q7, or R4H7 peptide develop less OT1 with effector phenotype, then mice having Tregs. [Jiný výsledek] |
| Tsyklauri Oksana, Preliminary results (figures). [Jiný výsledek] |