velikost textu
Výsledky projektu NK buňky v imunoterapii – cílení NKG2D receptoru
Výsledky
  Typ výsledku
Autor celku
Název celku(Celkem 2 zázn.)
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| Blažková Kristýna. The development of a high-affinity conformation-sensitive antibody mimetic using a biocompatible copolymer carrier (iBody). Journal of Biological Chemistry, 2021, sv. 297, s. 1–11. ISSN 0021-9258. IF 5.157. [Článek v časopise] This article published in the Journal of Biological Chemistry describes the development and characterization of conformationally selective polymer conjugates which target GCPII (Glutamate carboxypeptidase II), a prostate cancer marker that we commonly use as a model protein in our experiments. Although officially dedicated to a different GAUK project ( No. 1352219), this research was absolutely essential for the design and performance of the main project targeting the NKG2D receptor. |
| Beranová Jana. Tris-(Nitrilotriacetic Acid)-Decorated Polymer Conjugates as Tools for Immobilization and Visualization of His-Tagged Proteins. Catalysts, 2019, sv. 9, s. 1–11. ISSN 2073-4344. IF 3.444. [Článek v časopise] The article was published in the open access journal Catalysts in November 2019 within its special issue entitled Immobilization of Enzymes. In this work, a research exploring the binding of the so called iBodies targeted against His-tag is described. The technology developed in this experimental work is to be further applied within the project, namely for the development of alternative targeting strategies utilizing the binding of complete His-tagged proteins to iBodies as targeting ligands. |